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S Glyn-Jones

Publications and source records attributed to S Glyn-Jones.

7 recordsLinked to original sources
PubMed2006

RSA-measured inducible micromotion and interface modeling with finite element methods.

Osteolysis is the main cause of aseptic loosening and stem failure. The mechanism that leads to osteolysis is poorly understood; pressure generation caused by reversible stem micromotion may play an important role. We aimed to determine whether dynamically inducible micromotion occurs in vivo at the prosthesis-cement interface and to use these data to develop and confirm a finite element representation of this interface. Dynamically inducible micromotion was measured using radiostereometric analysis in 21 hips implanted with an Exeter stem, at 3 months and 12 months postoperatively, by changing loading from double-leg stance to single-leg stance. Dynamically inducible micromotion occurred at 3 and 12 months; similar micromotion was observed at both time points. At 3 months the head of the stem was displaced posteriorly (0.10 +/- 0.16 mm) and inferiorly (0.08 +/- 0.12 mm) on loading. A Coulomb friction nonbonded representation of the stem-cement interface was used to fit the clinically measured dynamically inducible micromotion. The final finite element model predicted gap opening and closing between the implant and the mantle. This may be a mechanism for generating pressure and distributing wear debris, which are believed to important contributors to failure.

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PubMed2006

The influence of surgical approach on cemented stem stability: an RSA study.

UNLABELLED: The surgical approach used is an important aspect of hip arthroplasty and will have an effect on the loading of the implant. Our goal was to establish whether there was a difference in early stem migration between the posterior and the lateral surgical approaches. The migration patterns of 45 Exeter stems in 45 patients were measured using radiostereometric analysis during a 2-year period; 19 of the stems were implanted using the posterior approach and 26 were implanted using the lateral approach. From postoperative radiostereometric measurements it was established that there was no difference in initial stem position between the two approaches. The posterior approach group had greater internal rotation of the stem, approximately 2 degrees during the first 2 years. The lateral group had almost 1/2 this amount of internal rotation. Overall stem subsidence was similar between the groups. These differences suggest that the lateral approach may give a survival advantage, especially for less rotationally stable stem designs and suboptimal cementing technique. The posterior approach gives rise to greater degree of internal rotation during the first 2 years. LEVEL OF EVIDENCE: Therapeutic Level II. See the Guidelines for Authors for a complete description of levels of evidence.

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PubMed2006

The premature failure of the Charnley Elite-Plus stem: a confirmation of RSA predictions.

We performed a clinical and radiological study to determine the rate of failure of the Charnley Elite-Plus femoral component. Our aim was to confirm or refute the predictions of a previous roentgen stereophotogrammetric analysis study in which 20% of the Charnley Elite-Plus stems had shown rapid posterior head migration. It was predicted that this device would have a high early rate of failure.We examined 118 patients at a mean of nine years after hip replacement, including the 19 patients from the original roentgen stereophotogrammetric study. The number of revision procedures was recorded and clinical and radiological examinations were performed. The rate of survival of the femoral stems at ten years was 83% when revision alone was considered to be a failure. It decreased to 59% when a radiologically loose stem was also considered to be a failure. All the patients previously shown in the roentgen stereophotogrammetric study to have high posterior head migration went on to failure. There was a highly significant difference (p = 0.002) in posterior head migration measured at two years after operation between failed and non-failed femoral stems, but there was no significant difference in subsidence between these two groups. Our study has shown that the Charnley Elite-Plus femoral component has an unacceptably high rate of failure. It confirms that early evaluation of new components is important and that roentgen stereophotogrammetric is a good tool for this. Our findings have also shown that rapid posterior head migration is predictive of premature loosening and a better predictor than subsidence.

Adult↗
PubMed2005

Influence of stem geometry on the stability of polished tapered cemented femoral stems.

Polished, tapered stems are now widely used for cemented total hip replacement and many such designs have been introduced. However, a change in stem geometry may have a profound influence on stability. Stems with a wide, rectangular proximal section may be more stable than those which are narrower proximally. We examined the influence of proximal geometry on stability by comparing the two-year migration of the Exeter stem with a more recent design, the CPS-Plus, which has a wider shoulder and a more rectangular cross-section. The hypothesis was that these design features would increase rotational stability. Both stems subsided approximately 1 mm relative to the femur during the first two years after implantation. The Exeter stem was found to rotate into valgus (mean 0.2 degrees , sd 0.42 degrees ) and internally rotate (mean 1.28 degrees , sd 0.99 degrees ). The CPS-Plus showed no significant valgus rotation (mean 0.07 [correction] degrees, sd 0.29 [correction] degrees ) or internal rotation (mean -0.03 degrees , sd 0.75 degrees ). A wider, more rectangular cross-section improves rotational stability and may have a better long-term outcome.

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PubMed2004

Roentgen stereophotogrammetric analysis of the Birmingham hip resurfacing arthroplasty. A two-year study.

The Birmingham hip resurfacing (BHR) arthroplasty is a metal-on-metal prosthesis for which no medium- or long-term results have been published. Despite this, it is increasing in popularity as an alternative to stemmed prostheses for younger patients. Since the fixation of the socket is conventional, the major concern is long-term failure of the femoral component. This can be predicted by the use of roentgen stereophotogrammetric analysis (RSA). We have therefore undertaken such a study of the BHR femoral component over a period of two years. Twenty patients (22 hips) underwent a standard BHR procedure. Migration of the femoral component was measured by RSA at intervals of three, six, 12 and 24 months. At 24 months the total three-dimensional migration of the head was 0.2 mm. This was not statistically significant. Previous studies have shown that implants which loosen quickly have rapid early migration. Our results therefore suggest that the BHR femoral component is an inherently stable device which is likely to perform well in the long term.

Adult↗
PubMed2003

The influence of cement viscosity on the early migration of a tapered polished femoral stem.

It is unclear whether it is best to use high-viscosity or low-viscosity cement for fixation of total hip replacement (THR) femoral components. This study examines the influence of cement viscosity on the migration of the Exeter femoral component using roentgen stereophotogrammetric analysis (RSA). Simplex, CMW1 and CMW3 G cements were examined in a total of 46 patients over a 12-month period. The overall pattern of migration for all cohorts was one of subsidence and rotation into valgus. There was no significant difference in any aspect of migration between the groups. In vitro studies demonstrate that low-viscosity cement forms a more stable bone-cement interface. Several groups have examined the in vivo effect of cement viscosity on stem longevity with conflicting results. For a polished, tapered implant that is designed to subside, cement viscosity does not influence the 1-year migration, and it is therefore unlikely to affect long-term outcome.

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