Biomedical subjects
Publications and source records attributed to S Gnot.
The class of admissible tests for Hardy-Weinberg equilibrium in a multi-allelic system is characterized. The standard goodness-of-fit chi-square tests is shown to be admissible for systems of two or more alleles. The conditional probability distribution required to determine the exact significance level of this test is presented.
Efficiency of three different methods: Bernstein's, maximum likelihood and determinant method were compared. A relative efficiency calculated as a ratio of variances of estimators was used for the comparison. It was shown that the determinant method is almost as efficient for estimating of recessive gene frequency as the method of maximum likelihood, and more efficient than the Bernstein's method.
The taxonometric methods of centrifugal correlation and principal components were used to classify sites along the investigated river with respect to quantity and quality of pollution. The degree of pollution was determined with the use of a collection of microbiological, hydrobiological and chemical characteristics selected by statistical methods.