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Biomedical subjects

S Grünstein

Publications and source records attributed to S Grünstein.

18 recordsLinked to original sources

Surgical treatment of varicocelle in oligospermic patients: a re-evaluation.

Left varicocele ligation was performed in 64 infertile men seen at our clinic during 1974-1978. High ligation of the left internal spermatic vein was done in all cases. The ages of patients were 23--46 yr. The criteria for operation were: palpatory findings of varicocele, primary or secondary infertility, and abnormal sperm analysis. Statistical analysis of the 3 main sperm parameters before and after surgery shows a significant increase in sperm count (P < 0.005) and motility index (P < 0.005), while the sperm morphology was not improved (P = 0.2). The pregnancy rate was 43.8%.

Adult↗

Etiological aspects of double monsters.

Four cases of double monsters are reported, including a rare case of craniofacial duplication (diprosopus). Based on the findings observed, etiological factors of these malformations are discussed. We suggest that exogenous (environmental) factors such as habits, way of life or religious practices of certain populations can influence the development of double monsters.

Abnormalities, Severe Teratoid↗

Epidural analgesia in labour performed by obstetricians.

The use of epidural analgesia by obstetricians in 2,645 women in labour is reported. The use of this technique as one of the routine methods is proposed even in those centres where no anaesthetist for pain relief is available for the 24-hour period. This is possible by the previous training of obstetricians. Advantages, side-effects and complications of epidural analgesia are discussed.

Anesthesia, Epidural↗

Human chorionic gonadotropin in intrauterine device users.

Measurements of human chorionic gonadotropin (HCG), luteinizing hormone (LH), and progesterone were carried out by means of radioimmunoassays in 21 women with regular menstruating cycles, using an intrauterine device (IUD). Serum HCG was undetectable in 10 women. In 11 women very small amounts of HCG were detected, all under 3 mIU/ml. HCG curves were inactive and flat; in one case the highest level of HCG coincided with the LH peak; in another case HCG was detected in spite of lack of ovulation. These facts suggest a cross-reactivity of LH and no real presence of HCG.

Adult↗

A technique for management of obstructed labour with antenatal fetal death.

A technique for management of obstructed labour associated with fetal death is presented. The new method makes it possible to decrease fetal head size by evacuation of brain tissue by suction using thoracic-type trocar. Three patients with obstructed labour and fetal death were managed successfully using this technique. The method permits a decrease of fetal head size easily and rapidly, avoiding the risks of other techniques. Moreover, its use makes it possible to eliminate craniotomy from obstetric practice. The method should be equally suitable for cases of major hydrocephaly.

Brain↗

The treatment of postmenopausal syndrome by monthly oral doses of quinestrol.

Seventy patients between the ages of 37 and 59 suffering from the menopausal syndrome were included in a clinical trial and treated for a period of 6 to 18 months. Out of the seventy, 43 were suffering from spontaneous and 27 from surgical menopause. Forty of them were given 1 mg of quinestrol and 30 received placebo. The drug was administered orally in a one-tablet dose once a month. An improvement took place in 35 (87.5%) of the women receiving quinestrol but in only 15 (50%) of those receiving placebo. Among the patients with spontaneous menopause an improvement was seen in 22 out of 25 (88%) receiving quinestrol, compared with 9 out of 18 (50%) receiving placebo. Tolerance of the drug was good and most of the laboratory tests as well as blood pressure and body weight showed statistically non-significant changes. This kind of treatment is expecially suitable when daily intake is undesirable.

Administration, Oral↗

Extramembranous pregnancy: a case report.

A rare case of extramembranous pregnancy is reported. It was associated with intermittent loss of liquor and bloody discharge beginning at about the 25th week of gestation. An anencephalic infant was delivered alive from a breech presentation during the 31st week of gestation. The placenta was markedly circumvallate, with short, thick membranes which did not cover more than 10% of the infant. The course of the pregnancy and the examination of the infant and placenta are discussed, and the pertinent literature is reviewed.

Adult↗

Epidural analgesia during labour in twin pregnancy.

We report on the use of epidural analgesia during labour in 58 out of a total of 234 twin deliveries performed over a five-year period. A comparable control group consisted of 44 twin pregnancies delivered consecutively during the year preceding the introduction of epidural analgesia into our department. Epidural analgesia shortened the mean time of labour and made possible the performance of all necessary instrumental and obstetrical manoeuvres, without additional anaesthesia or adverse effects on the second twin. The epidural group required oxytocin more often due to an increased incidence of hypotonic uterine dysfunction. There was also a considerable increase of instrumental deliveries in the epidural group. The condition of the newborn infants of both groups, evaluated by Apgar score at one minute, was similar, but there was a higher perinatal mortality among pre-term infants delivered under epidural analgesia. Epidural analgesia was found to be an acceptable method of relieving pain in twin labour, but because of the increased necessity to use oxytocin and the relatively high perinatal mortality observed among pre-term infants, further experience is necessary before it can be claimed that this is the method of choice for relief of pain in twin labour.

Anesthesia, Epidural↗

Fertility following adnexal surgery.

A total of 154 patients after adnexal operations between 1969-1973 were queried in order to establish fertility rate after operation. Out of the 154 questioned 122 submitted their reply. i.e. 69.2 per cent. These women were divided into three groups. The first one comprised 46 patients operated because of extrauterine pregnancy, the second consisted of 50 patients operated because of ovarian cyst and the third one included 18 women operated because of bilateral adnexal pathology. In the first group 90 per cent of the patients who desired so succeeded to become pregnant. In the second group 87 per cent succeeded and 66.6 per cent in the third group. The possible ethyological factors of sterility after adnexal operations were discussed and conservative operations were proposed as the most convenient policy in cases of bilateral adnexal pathology.

Adnexa Uteri↗

Epidural analgesia in midtrimester abortion.

Epidural analgesia was performed in 78 women with abortion in the midtrimester or pre-term delivery of up to 27 weeks of pregnancy. The patients were divided into three groups. The first group included thirty women with signs of inevitable abortion. The second group comprised of 9 cases of induced abortion and the third one of 39 cases of pre-term delivery. The three groups were statistically evaluated in relation to time of abortion or labor, fetal weight, weeks of pregnancy, parity and patient's age and were consequently compared with 90 women divided into three similar control groups. The effect of the epidural analgesia was satisfactory in all cases in the three experimental groups, and no complications or side-effects were observed. The advantages of the use of epidural analgesia were the diminished psychological reaction to the abortion, the possibility to perform surgical procedures without any additional anesthesia and the reduction in the duration of the abortion or labor. These advantages justified in our opinion the use of the procedure.

Abortion, Induced↗

Trisomy-D in a cyclops with cardiovascular defects.

A case report of cyclops with trisomy-D in a female infant, associated with cardiovascular defects is presented. A survey of the literature pertaining to other reported cases of cyclopia is presented to establish the probablity of the existence of at least two distinct etiologic groups of cyclopia--those associated with trisomy-D and those associated with other chromosomal aberrations, single gene mutations, or non-genetic factors.

Abnormalities, Severe Teratoid↗

Radiological visualization of Gartner's duct cyst.

During hystero-salpingography a sharply outlined collection of contrast medium was observed near the cervical canal of the uterus and interpreted as filling of a Gartner's duct cyst, an observation that- to the best of our knowledge-has not yet been reported as a radiological finding.

Adult↗