Biomedical subjects

S Graham

Publications and source records attributed to S Graham.

At least 307 records · Page 17Linked to original sources

PubMed1975

Low-fiber intake as an etiologic factor in cancer of the colon.

A case-control dietary study of 198 patients with cancer of the colon and two matched control groups demonstrated a significantly lower fiber consumption frequency among the cancer patients. This difference was not confined to a few items. Of the 73 items on the fiber list, 61 were eaten less often by the cancer patient than by a neighborhood control, and 57 were consumed less frequently than by a surgical control. These findings support the hypothesis that low-residue foods play an etiologic role in colon carcinogenesis. A mechanism related to the possible potential carcinogenic properties of degraded biliary compounds may be implicated.

Adult↗

PubMed1975

Future inquiries into the epidemiology of gastric cancer.

The fact that gastric cancer has been shown in many studies to be strongly related to a large number of social factors, ethnic background, occupation, socioeconomic status, and the like, suggests the importance of exogenous factors in its etiology. Past studies show a variety of relationships that furnish leads requiring elucidation to further understanding of this disease, e.g., higher risks related to exposures to asbestos, metals dusts, purgatives, and poor dental hygiene. Diet inquiries have steadily improved and negative relationships have been discovered with ingestion of vegetables in studies in Wales, Liverpool, Buffalo, Honolulu, Japan, and Norway. Positive relationships with starch have been found in many of these same places as well as in Israel. These leads need further investigation, as do better methods of diet research, studies of diet and histological type of gastric cancer, diet in its relationship to familial aggregation of gastric cancer, and studies of consistencies in relationships among the various sites in the digestive tract. Because diet is so heterogeneous in modern societies, multivariate analysis is needed in addition to simpler traditional modes.

Alcoholism↗

PubMed1975

Positron ranges obtained from biomedically important positron-emitting radionuclides.

Positron ranges were obtained experimentally for several nuclides used in scintigraphic imaging. The nuclides examined were 13C, 13N, 15O, 18F, 68Ga, and 82Rb. The results are discussed with respect to the ultimate spatial resolution obrained in a scintigraphic image.

Carbon Radioisotopes↗

PubMed1974