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Biomedical subjects

S Gulmen

Publications and source records attributed to S Gulmen.

At least 19 recordsLinked to original sources

Cementomas--aggressive or innocuous neoplasms?

No class of tumor is so inadequately discussed in the otolaryngology literature as the "cementomas". Until recent years, four distinctly different benign fibro-osseouslesions containing cementum were clumped together under the heading of cementoma. The separate entities in this tumor class are benign cementoblastoma (true cementoma), cementifying fibroma, peripical cemental dysplasia, and gigantiform cementoma (florid osseous dysplasia). Only an occasional case of the gigantiform variant or an unusually aggressive cementifying fibroma requires an extensive operation for complete excision.

Adolescent

Cementomas. II. Aggressive cemento-ossifying fibroma of the ethmoid region.

Aggressive cemento-ossifying fibroma is the most aggressive tumor of all cementum-containing neoplasms. An extensive, destructive cemento-ossifying fibroma of the ethmoid region was found in a patient. To our knowledge, this is the first case of a cemento-ossifying fibroma in this location. A radical maxillectomy was ultimately required to control the tumor, preserving orbital contents. The unique site of origin is thought to be the result of an ectopic periodontal membrane or of a primitive mesenchymal cell rest.

Adult

Sweat gland carcinoma of the lips.

Sweat gland carcinomas are extremely rare tumors with a fully malignant potential. Two cases of primary sweat gland carcinoma of the lips are presented. Because of the unique nature of this lesion, the histopathology and biologic behavior are discussed, and the pertinent literature is reviewed.

Adenocarcinoma

An investigation concerning tumor cell antigenicity of hamster malignant melanoma utilizing heterologous antiserum.

The antigenic potential of spontaneous malignant melanoma of the Syrian hamster was investigated. Antisera to the tumor were prepared in two groups of rabbits; one group was immunized with tumor homogenate material and the other with tissue cultured tumor cells. The antiserum was absorbed with normal hamster tissue extracts and serum to remove cross-reacting antibodies. The presence of tumor specific antibodies was demonstrated using immunodiffusion and fluorescent antibody staining techniques. Tumor specific antiserum prepared in this manner gave a single precipitin line against tumor tissue in gel-diffusion tests, and showed specific staining of tumor cells in the fluorescent antibody test.

Animals