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Biomedical subjects

S H Hay

Publications and source records attributed to S H Hay.

9 recordsLinked to original sources

Use of a new generation ophthalmoscope.

A new optical configuration for an ophthalmoscope is a hybrid of the present direct and indirect instruments, combining the strengths of both to increase overall efficiency. Cross polarization is used as a means of reducing glare and increasing clarity of detail. A fiberoptic light source increases light intensity, but reduces heat, weight, and inconvenience. These characteristics result in a self-contained, handheld indirect instrument. This ophthalmoscope is mechanically aligned and therefore easy to use. Both ophthalmologist and nonophthalmologist may find this instrument of benefit in ocular examinations.

Eye Burns↗

Retinal reflex photometry as a screening device for amblyopia and preamblyopic states in children.

Aberration in the physical structure or alignment of the eyes may produce pathologic neurocompensatory changes in the brain that, if left unattended, become irreversible. Two common examples of this abnormal state are accommodative esotropia and amblyopia. Both have a large optic component in their etiology and in most cases are correctable by optic methods. Generated retinal reflex photometry is a screening method that can detect, in the eyes of children, optic defects that tend to be the antecedents of more serious neurocompensatory processes. Detection at an early age permits more effective management and treatment of amblyopia. This technique is fast, safe, and inexpensive and provides a permanent record. It requires no response from the subject except a modicum of cooperation. It is attractive as an ocular screening method because it does not require highly trained personnel to administer the examination, yet appears to be accurate. The results lend themselves to mechanized processing.

Age Factors↗

Smith-Lemli-Opitz syndrome: neuropathological and ophthalmological observations.

The case of a three-year-old boy with the Smith-Lemli-Opitz syndrome is reported. In addition to the constellation of skeletal and genital anomalies classically described in this syndrome, this patient had spontaneous opsoclonus-like eye movements, strabismus, lack of visual following responses and of opticokinetic reflexes. At autopsy the cerebellar vermis was found to be absent. There were retinal hemangiomas. Microscopical examinations showed loss of Purkinje cells and extensive neuronal degeneration within dentate nuclei, associated with patchy demyelination of cerebellar peduncles and central white matter. These findings may contribute to the explanation of the pathophysiology of opsoclonus and some of the neuro-ophthalmological findings.

Abnormalities, Multiple↗

Anaemia of pregnancy: the changing postwar pattern.

A popluation survey covering over a quarter of a century has shown clearly the improvement in haemoglobin levels in women attending antenatal clinics at the Glasgow Royal Maternity Hospital. Various influences have helped to bring this about, foremost among these being routine early prophylaxis with combined iron and folate supplements. Indeed, a time-space relationship between changes in prophylactic therapy, rates of improvement, and the incidence of megaloblastic anaemia can be shown. The women at risk are still essentially the same except for a new group of young, unmarried girls, who must be watched. In our view the withdrawal of routine prophylactic therapy in pregnancy would be retrograde step.

Adult↗