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S H Kaempfer

Publications and source records attributed to S H Kaempfer.

12 recordsLinked to original sources

Ten years of experience with semen cryopreservation by cancer patients: follow-up and clinical considerations.

Antineoplastic damage to the testicular germinal epithelium with accompanying infertility or subfertility is now a recognized indication for the use of sperm banking. Thus, issues concerning quality of life now compete with questions of survival in decisions made in oncologic settings. In an attempt to learn what concerns patients who use semen preservation facilities, a 10-year retrospective study was undertaken. Registered mail and phone solicitation was used to determine follow-up characteristics of self-referred male cancer patients who voluntarily banked semen at a private facility before they began cancer treatment. The difficulties encountered in conducting follow-up on this group of patients raise questions about sperm banking practices by cancer populations.

Attitude↗

An interdisciplinary, interagency, primary care approach to case management of the dually diagnosed patient with HIV disease.

The epidemic of dually diagnosed patients with HIV disease (HIV disease coexisting with substance abuse and/or mental illness) has become increasingly recognized. This phenomenon poses potential threats to the effectiveness of HIV primary care, even when delivered by expert clinicians. This article describes implementation strategies for the provision, documentation, and third party billing of interdisciplinary, interagency HIV primary care case management within the context of an academic medical center. Our approach, which is specific to our setting, has evolved as we have attempted to define an active role for the primary care physician as a member of the case management team.

Academic Medical Centers↗

Effect of dronabinol on nutritional status in HIV infection.

OBJECTIVE: To examine the effect of dronabinol (delta-9-tetrahydrocannabinol) on appetite and nutritional status in patients with symptomatic HIV infection and weight loss. DESIGN: Double-blind, randomized, placebo-controlled, crossover trial with two five-week treatment periods separated by a two-week washout period. Patients received dronabinol 5 mg twice daily before meals or placebo. SETTING: A university-based HIV/AIDS clinic and a large infectious disease private practice largely devoted to care of patients with HIV. PARTICIPANTS: Twelve HIV-infected patients who had had at least a 2.25-kg weight loss participated in the study. Five patients completed the protocol, and seven withdrew (two because of drug intolerance, two because of disease progression, two because of noncompliance, and one because of experimental antiretroviral therapy). MAIN OUTCOME MEASURES: Main outcome measures included caloric intake, weight, percent body fat, serum prealbumin, and symptom distress. RESULTS: During dronabinol treatment, subjects experienced increased percent body fat (one percent, p = 0.04); decreased symptom distress (p = 0.04); and trends toward weight gain (0.5 kg, p = 0.13), increased prealbumin (29.0 mg/L, p = 0.11), and improved appetite score (p = 0.14). CONCLUSIONS: In a selected group of HIV-infected patients with weight loss, short-term treatment with dronabinol may result in improvement in nutritional status and symptom distress.

Adult↗