PubMed Health⌕ Search

Biomedical subjects

S H Lerman

Publications and source records attributed to S H Lerman.

6 recordsLinked to original sources
PubMed1981

Gastric and pyloric motor response to sympathetic nerve stimulation after chemical sympathectomy.

This study evaluated the effect of electrical stimulation of the greater splanchnic nerve on gastric and gastroduodenal motility in 6-hydroxydopamine (6-OHDA)-pretreated anesthetized dogs. Biopsies from the stomach, pylorus and duodenum were obtained and analyzed by catecholamine fluorescence microscopy. Degeneration of adrenergic terminals in Auerbach's plexus was complete at 1 week. The majority of stimulations in control dogs or dogs treated with 6--OHDA produced contractions in the gastric body, antrum, and pylorus and relaxation of inhibition in the duodenum. The excitatory motor responses in the gastric body, antrum and pylorus were unaffected by the administration of hexamethonium. Following atropine administration, contractions due to splanchnic nerve stimulation virtually were abolished in the antrum, pylorus and duodenum and were reduced in number in the gastric body. Relaxation and inhibition were no longer observed in the duodenum after atropine. The greater splanchnic nerve appears to contain both excitatory are inhibitory cholinergic pathways to the musculature of the stomach, pylorus, and duodenum.

Animals↗
PubMed1981

Spontaneous idiopathic hematoma of the spermatic cord: a report of 2 cases.

We present 2 cases of spontaneous idiopathic spermatic cord hematoma and review the literature. These hematomas predominately occur in untraumatized young adults after physically stressful exercise. Surgical exploration was performed in 4 previously reported cases and our own. In each case the preoperative diagnosis was incorrect. Since this clinical entity cannot clearly be distinguished from other causes of an acute scrotum surgical exploration seems warranted. Possible etiologies of spontaneous idiopathic spermatic cord hematoma are spermatic cord vein rupture and tear in the cremasteric muscle.

Adult↗
PubMed1981

Pyloric motor response to sympathetic nerve stimulation in dogs.

Through this study we evaluated the effect of electrical stimulation of the greater splanchnic nerve on gastroduodenal motility in anesthetized dogs. The majority of stimulations (at a frequency of 10 Hz for 5 msec at a strength of 10V for a train of 10 sec) produced contractions in the gastric antrum and pylorus and relaxation in the duodenum. The antral, pyloric, and duodenal motor responses were unaffected by cervical vagosympathectomy, thoracic vagotomy, and adrenalectomy. Administration of phentolamine, propranolol, or hexamethonium and pretreatment with reserpine failed to affect the contractile gastroduodenal motor response. The inhibitory motor response in the duodenum was also unaffected by these surgical procedures and administration of drugs. After atropine administration, contractions induced by splanchnic nerve stimulation were abolished in the pylorus, as well as in the antrum and duodenum. Tetrodotoxin also abolished the gastroduodenal motor response. The greater splanchnic nerve contains an excitatory cholinergic pathway to the musculature of the pylorus.

Animals↗