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Biomedical subjects

S H Mohammed

Publications and source records attributed to S H Mohammed.

16 recordsLinked to original sources
PubMed1995

Circulating growth hormone (GH), insulin-like growth factor-I (IGF-I) and free thyroxine, GH response to clonidine provocation and CT scanning of the hypothalamic-pituitary area in children with sickle cell disease.

Serum growth hormone (GH), cortisol, free thyroxine (FT4), thyroid-stimulating hormone (TSH), and insulin like growth factor I (IGF-I) concentrations were measured in 15 children with sickle cell disease (SCD) together with their heights < 5th percentile for age and gender, and in 15 healthy age-matched children who had normal variant short stature (NVSS). GH response to an oral dose of clonidine (0.15 mg/m2) and cortisol response to ACTH stimulation were determined in the two groups. Children with SCD had significantly lower serum concentrations of IGF-I and decreased GH response to stimulation. Eight out of the 15 children with SCD did not mount an appropriate GH response to clonidine provocation (> 10 micrograms/l). CT scanning of the hypothalamic-pituitary area in those eight children with SCD revealed a partial or complete empty sella in all of them. It appears that defective GH release, and consequently low IGF-I production and slow growth velocity in children with SCD might be secondary to hypoxic-vascular insults to their hypothalamic-pituitary axis during one or more of the sickling episodes.

Case-Control Studies↗
PubMed1992

Chronic granulomatous disease with renal stones.

A case of chronic granulomatous disease with hydronephrosis and renal calculi is presented. This is to our knowledge the first such case to be reported. The calculi were successfully ablated by extracorporeal shockwave lithotripsy.

Child↗
PubMed1988

Balloon catheter dilatation of urethral strictures.

Seven patients with urethral strictures due to different causes were treated by balloon catheter dilatation. The dilatation was performed on an outpatient basis in conjunction with suprapubic voiding cystourethrography and under fluoroscopic control. Only diazepam sedation and topical anesthesia were used. No indwelling catheters were placed in the urethra after the procedure. Six of the seven patients have been followed for 6-26 months, and only two have required redilatations. There have been no complications that required therapy. The initial success with our technique and that reported by others suggest that balloon catheter dilatation offers a good alternative treatment for urethral strictures to replace bouginage, urethrotomy, and urethroplasty.

Adolescent↗
PubMed1988

Management of obstructive small-bowel lesions.

By means of a 350 cm long intestinal tube with a balloon at its distal tip, surgically significant stenoses of the small intestine can be selectively identified and differentiated from changes not requiring surgical intervention. The balloon is inflated with 40 ml of air at the site of the obstruction, thereby serving as a marker for the surgeon in order to limit the intervention and avoid complications due to unnecessary manipulations. The tube offers a significant improvement in the management of chronic intestinal obstructive disease. Details of the technique and results from successful use in 24 patients are presented.

Catheterization↗
PubMed1986

Dislodgement of impacted oesophageal foreign bodies with carbonated beverages.

Carbonated beverages release sufficient carbon dioxide when ingested, to distend the oesophagus, relax the lower oesophageal sphincter and to force the passage of impacted meat and other foreign bodies into the stomach. Of 28 patients with foreign bodies in the oesophagus, eight had them dislodged after ingestion of barium sulphate suspension, whereas carbonated soda water was used successfully in 16 out of 20 patients with a normal oesophagus or with oesophageal motility disorders and organic strictures. Carbonated beverages may be used as the first-line treatment of acute episodes of oesophageal obstruction due to foreign bodies and could also be integrated into the long-term management of oesophageal disease.

Adult↗
PubMed1985

Andrew's liver salt as an effervescent in upper gastrointestinal radiography.

Double-contrast radiography is widely used for examination of the upper gastrointestinal tract. However, it is not practiced routinely in many developing areas, partly because of high cost of the effervescent agents. In a series of 300 upper gastrointestinal tract investigations, Andrew's Liver Salt has proven to be an effective effervescent, releasing adequate gas in more than 80% of the examinations. It disintegrates rapidly with minimal bubble formation and no artifacts. It has high patient acceptability and is very inexpensive.

Barium Sulfate↗
PubMed1982

Erosive gastritis.

Erosive gastritis is a well-defined radiologic and endoscopic entity. It is one of the common causes of upper gastrointestinal bleeding, yet it is seldom diagnosed and often confused with a number of other diseases. This communication re-emphasizes the characteristic endoscopic and radiologic features of erosive gastritis and its differential diagnosis. Two representative cases are reported.

Diagnosis, Differential↗
PubMed1977

Double contrast examination of the stomach. An improved technique.

Double contrast examination of the stomach has a greater accuracy than conventional barium meal, especially in the diagnosis of minor gastric lesions. The use of a common drinking straw with a side-hole to introduce air simultaneously with the barium suspension after gastric emptying with metoclopramide and using short acting hypotonic agents like Buscopan and Glucagon provides a practical and effective simplified technique for double contrast examination of the oesophagus, stomach and duodenum.

Adolescent↗
PubMedDate not supplied

Suprapubic micturition cystourethrography.

Suprapubic micturition cystourethrography is performed by puncturing the bladder aseptically, in the midline, 1 to 2 cm above the symphysis pubis with an 18 to 21 gauge needle. The needle is pointed 10 to 15 degrees cranially to avoid puncture of the trigonum and urethra. Anaesthesia, antibiotic protection, and diuretics are not necessary. In 225 examinations performed on 200 patients, the only complications noted were transient haematuria (1.5%) and slight extravasation of contrast medium through the puncture sites (8%). None required any therapeutic measures. In 4 patients puncturing of the bladder needed ultrasound guidance. The technique is ideal for the study of vesicoureteral reflux, neurogenic bladder, urethral strictures, posterior urethral valves and other urethral pathology. It is also useful in balloon catheter dilatation of urethral strictures. Suprapubic micturition cystourethrography is safe, efficient and time-saving. It is well accepted by the patients and carries little risk of urinary infection.

Adolescent↗