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Biomedical subjects

S H Shah

Publications and source records attributed to S H Shah.

16 recordsLinked to original sources

Incidence of pulmonary nodules detected by computed tomography in patients with bronchial carcinoma.

Computed tomography (CT) is more sensitive in detecting pulmonary nodules than conventional chest radiography. The incidence of pulmonary nodules on thoracic CT scans, not visible on chest radiographs, in patients with small-cell carcinoma of the bronchus (SCCB) was 27%, and in patients with non-small-cell carcinoma (non-SCCB) the incidence was 28%. Some of these nodules may be malignant. This has implications for the surgical staging of patients with lung cancer in the United Kingdom, where there is a lower incidence of benign granulomatous nodules than in the USA.

Carcinoma, Bronchogenic

Radiological abnormalities in temporal lobe epilepsy with clinicopathological correlations.

In 73 patients with drug-resistant temporal lobe epilepsy submitted to an unilateral anterior temporal lobectomy the radiographs were studied to see if there were any correlation with the pathology subsequently found and with the outcome of the operation. A small middle cranial fossa, focal calcification, and temporal horn displacement are often better indices of the underlying pathology than temporal horn dilatation alone. In a small number of cases, however, radiological changes were seen on the side opposite to an unilateral EEG focus, thus suggesting bilateral disease.

Adolescent

Analysis of 105 uninodular goitres.

Data on 105 solitary thyroid nodules, confirmed at surgery to be solitary, is presented. Six (5.7%) were malignant, 4 papillary and 2 follicular. The sensitivity and the specificity of 131I radionuclide thyroid scan (n = 90) were 100% and 24% respectively. Similarly, the sensitivity and specificity of fine needle aspiration cytology (n = 65) was 75% and 100% respectively. In both instances, the "gold standard" was the histopathology of the surgically removed nodule. In order to avoid unnecessary surgery, without missing malignancy, we would recommend the combination of radionuclide thyroid scan and FNAC for investigation of solitary thyroid nodules.

Adult

Association of oral carcinoma with nasswar (snuff dipping).

A total of 186 cases of oral carcinoma were treated at the Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, and at the District Headquarter Teaching Hospital, Abbottabad, during a two-year period. These patients were investigated for their personal habits and environmental factors. Use of nasswar was the most significant habit. We found that 91% of patients had the habit of nasswar dipping for more than 10 years. A history of tobacco smoking was noted in 44% of cases. Of these, 96% were also nasswar addicts. A significant correlation of the oral lesions was found with the site of the nasswar (snuff) dipping. We concluded that nasswar and other types of smokeless tobacco are not safe alternatives to tobacco smoking.

Adult