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Biomedical subjects

S Haase

Publications and source records attributed to S Haase.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Radiocephalometric findings and duration of snoring in habitual snoring and obstructive apnea syndrome].

In 11 patients with chronic snoring and 12 subjects with obstructive apnoea syndrome the percentage of snoring duration above a preset sound pressure level during one night's sleep was correlated with the radiocephalometric data. Cephalometric distances PAS, PM-Pg, MP-H and angles SNA and SNB representing measures for posterior airway space, size of soft palate, relative position of hyoid bone and relative position of maxilla and mandibula were evaluated. Each patient showed pathological deviations from normal values in at least one of the cephalometric parameters. A significant correlation between snoring duration and a single cephalometric distance could not be found. However, an index combining pathological deviations from all three cephalometric distances showed a highly significant correlation with snoring duration (p less than 0.01 - Fig. 11), as did deviations from normal values of angle SNB (p less than 0.03 - Fig. 10). Our findings indicate that snoring and obstructive apnoea syndrome are not only caused by neurologic dysregulation, and that in addition specific craniofacial anomalies are prerequisites for the development of the disease. For the first time it is demonstrated that these anomalies exist in chronic snorers as well as in apnoeic patients. Our findings support Lugaresi's hypothesis that heavy snoring and obstructive apnoea syndrome are based on the same defect and differ in severity only.

Adult↗
PubMed1988

[Nasal speech with special reference to a submucous cleft palate].

Nasal speech, which is in many cases the first and only sign of many different diseases, is frequently misinterpreted by the otolaryngologist who examines the patient first. This is demonstrated by an analysis of 23 patients having a submucous cleft palate. A simple diagnostic procedure is suggested that enables the clinician to distinguish between different forms of nasality, its underlying causes and localisation.

Child, Preschool↗
PubMed1987

[A skull with deformed nasal structure from the 17th century].

A skull from the baroque period is presented which attracted our attention because of its round piriform aperture and enlarged nasomaxillary bones. The deformity is very probably due to large nasal polyps. Some medical documents in literature and an oil-painting with the portrait of an old woman with a bloated nose from the 17th century show that this type of nasal disease was well known three hundred years ago.

Adult↗
PubMed1986

[Phases of postnatal nasal growth. A critical review].

This review evaluates anatomical, anthropological, and radiographic cephalometric data of the growing nasomaxillary complex, with special regard to their reliability and value for therapy planning. Within the two post-natal years and during puberty parts of the nose grow faster than during other periods of life. After the second decade there is still some growth measurable in some nasal parts up to an advanced age.

Adolescent↗
PubMed1985

[Value of computerized tomography in the diagnosis of recurrence in malignant head and neck tumors].

Among 441 CT scans of 303 patients with a malignant tumor of the head or neck 138 scans of 83 patients were performed for evaluation of recurrent tumor. In diagnosing nodal recurrence computed tomography (CT) had a sensitivity of 92% (52 out of 56) and a specificity of 96% (55 out of 57). In diagnosing recurrence at the primary site sensitivity of 72% (56 out of 77) and specificity of 60% (30 out of 50) was lower and clearly inferior to physical examination with 92 and 88% respectively. CT was very useful in delineating advanced recurrencies, especially in regions that were not readily accessible by physical examination or were indurated by flat scarring. In addition to the complete staging of nodal involvement this makes CT the radiologic method of choice in follow-up of patients with malignant tumors of the head and neck. A post-therapeutic baseline scan obtained 6-8 weeks after surgery resp. radiotherapy is expected to further improve results, especially in differentiating scar from recurrent tumor.

Adult↗
PubMed1984

[Value of computer tomography in the detection of regional lymph node metastases, of malignant tumors in the area of the head and neck].

CT is very suitable for showing cervical lymphatic spread in malignant tumors of the head and neck. The regional lymph-node areas of 123 patients with histologically proven malignant tumours of the oral cavity, hypopharynx and larynx were evaluated in a prospective study. Clinical examination, CT-findings and pathological work up of the surgical specimens were comparatively analysed in 53 patients. The proportion of false negative lymph-nodes on palpation was 21%. This error could be reduced by the use of CT to 7.5%.

Carcinoma↗
PubMed1983

[Computed tomography of cervical lymph node metastases in malignant tumors of the head and neck region].

The lymphatic spread in 123 patients with biopsy-proven malignant head and neck tumors was evaluated by CT in a prospective study. In 53 cases, clinical examination, CT and pathological-histological work-up of the surgical specimens were comparatively analysed. The fraction of false-negative judged lymph nodes by palpation was 21%. This high error in judgement could be diminished to 7.5% by the use of CT. 83% of squamous cell metastases showed a central decrease in density due to necrosis after intravenous infusion of contrast material.

Carcinoma, Squamous Cell↗
PubMed1982

[The value of computed tomography in the diagnosis of malignant oral tumors and their local metastases (author's transl)].

Forty-six computed tomographic examinations on 39 patients with histologically confirmed malignant oral tumors are reported on. The value of information by CT is compared to clinical staging in 24 operated cases. In determination of the T-category, clinical examination is superior to CT. The local metastases and the outline of the tumor are better diagnosed by CT. Provided that a subtle examination technique is used, CT can be of great help to the surgeon in choosing the adequate therapy in oral malignant tumors.

Adult↗
PubMed1979

[Relationship between pathological changes in the lipid and protein metabolism and the occurrence of odontogenic jaw cysts].

Compared with a control group, cholesterol and triglyceride values are significantly elevated (chi2 = 14.52 and 21.65) in patients with odontogenous cysts. No statistically significant difference could be established in terms of the enzyme work-up (lipase). No statistically significant differences could be established in fractions of protein metabolism via electrophoresis.

Adult↗
PubMed1978

Red cells and gelatin as the core of a unified program for the national procurement of blood components and derivatives. Prediction, performance, and impact on supply of albumin and factor VIII.

The use of a gelatin plasma substitute as an integral part of a unified national program for the procurement of blood components and derivatives paves the way for the extensive use of red cell concentrates in the treatment of hemorrhage, the plasma from the original donations being partly diverted to the fractionation program of a national transfusion service. We estimated the potential of such a system paced by the demand for red cells and predicted that the use of 20% of fresh whole blood and 80% concentrates would not increase the demand for albumin, the yield of which would suffice to cover three-quarters of current needs in our country. The actual performance of a program using 85% of red cell concentrates in a university hospital with an exceptionally high incidence of major hemorrhage was analyzed in detail. The use of albumin per unit of transfused red cells rose by 9%. With a nationwide increase of this magnitude, 67% of the demand in our country could still be met and the estimated true need for albumin of 200 kg per million inhabitants and year would be fully covered. The yield of factor VIII is 200--300% of the demand. The determinants of the effects of such a system vary from country to country, but its fundamental potential is obviously considerable.

Blood Proteins↗