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Biomedical subjects

S Hancke

Publications and source records attributed to S Hancke.

At least 37 records · Page 2Linked to original sources
PubMed1990

Atherosclerosis in native Greenlanders. An ultrasonographic investigation.

A low frequency of ischemic heart disease in Eskimos (Inuit) has been regarded as an expression of absent or low atherosclerosis. The true extent of atherosclerosis in the Eskimo populations of the World is not known due to low autopsy activity. In order to register atherosclerotic changes in the carotid and femoral arteries 61 Native Greenlanders from two settlements with a traditional Eskimo life style in the Uummannaq district of Northwestern Greenland were examined ultrasonographically with a portable scanner (Aloka) using a 7.5 MHz 4 cm linear array transducer. The results obtained were compared to an age and sex matched urban control group of 122 Danes from Copenhagen. The investigation showed that the Native Greenlanders had almost the same degree and extent of atherosclerosis in the carotid and femoral arteries as the Danes. Thus, the low incidence of ischemic heart disease in Native Greenlanders may not be attributed to lesser atherosclerosis. Further studies, particularly autopsy studies are needed.

Adult↗
PubMed1988

Popliteal venous aneurysm.

A case of popliteal venous aneurysm in a 69-year-old male is presented. Although rare these aneurysms are potential sources of thromboembolism indicated by the fact that they are most often discovered in patients with a history of recurrent pulmonary embolism. The aneurysm was successfully treated by simple surgical resection and a short course of oral anticoagulants.

Aneurysm↗
PubMed1987

The reliability of transabdominal ultrasound scanning in the determination of prostatic volume. An autopsy study.

The prostatic volume as determined by transabdominal ultrasound scanning using the ellipsoid method was compared to the prostatic volume determined by autopsy in 26 post-mortem men. The regression line was nearly optimal (Y = 1.06 chi + 0.57) although it seems that ultrasound underestimates prostatic volume slightly. The parametrical correlation coefficient was 0.86 and the non-parametrical Spearmans rho was 0.76. It is concluded that transabdominal ultrasound scanning has a definite value in the assessment of prostatic size.

Aged↗
PubMed1986

Hepatosplenomegaly in infectious mononucleosis, assessed by ultrasonic scanning.

The present study aims at an assessment of hepato-splenomegaly in infectious mononucleosis (IM). In 29 patients admitted to the ENT department with IM, based on the typical clinical and laboratory findings, including a positive mononucleosis test in most cases, the size of the liver and spleen was estimated by ultrasonic scanning on days 1, 3, 5, 10, 20, 30, 90 and 120 after admission. A control group of eight patients with peritonsillar abscess was included for comparison. The results showed that all patients had an enlarged spleen (mean enlargement: 50-60 per cent) but only a few were palpable. Half of the patients had enlargement of the liver (5-20 per cent), which was palpable in only 8 per cent. There was no correlation between the size of the spleen and that of the liver, not between the changes in the size of these organs. There was no enlargement of the liver or spleen in the control group. No correlation was found between the size, or changes in the size, of the organs and blood values such as lactatdehydrogenase and aspartatamino-transferase. There is, however, a striking parallelism between the curves for these parameters, which might indicate that the organs as well as the blood tests return to normal within 28 days. If this holds true, our warning to abstain from physical exercise and alcoholic intake may be limited to a period of about 1 month.

Adolescent↗
PubMed1986

Ultrasonic demonstration of clinical and subclinical hepatic venous thrombosis in paroxysmal nocturnal haemoglobinuria.

Extensive hepatic venous thrombosis was demonstrated by ultrasonic scanning in three patients with paroxysmal nocturnal haemoglobinuria (PNH). The ultrasonography results were confirmed by X-ray venography. Two of these patients were without clinical symptoms of hepatic involvement apart from a slight increase in transaminases. This study indicates, firstly, that ultrasonic scanning is a rapid and reliable diagnostic tool in monitoring patients for this serious and often fatal complication, and, secondly, that hepatic venous thrombosis may be a more common complication in PNH than previously assumed.

Adult↗
PubMed1984

Non-hydrolysed and hydrolysed soy protein. A human immunological study.

Daily consumption of soy protein has increased during recent years. Twelve healthy subjects and 12 atopic patients were given 30 g non-hydrolysed soy protein (NHS) or 30 g hydrolysed soy protein (HS) daily during a 3-month period. There were no changes in the following immunological parameters: IgE with specificity for NHS or HS, IgG with specificity for NHS, crossed radioimmunoelectrophoresis with NHS and skin prick test using NHS or HS. Hypertrophy of the pancreas in rats exposed to excessive peroral intake of soy flour has been reported. In our study the size of the pancreas was measured before dosing began and at the end of the study by means of ultrasound. No change in size was shown. Daily intake of 30 g NHS and 30 g HS gave rise to gastrointestinal discomfort, while 15 g of both soy protein preparations were usually accepted.

Adult↗
PubMed1984

Ultrasonically diagnosed simple cysts of the liver.

In 26 patients simple cysts of the liver were diagnosed by ultrasonography. Half of the patients had no symptoms, and half presented with abdominal pain and a palpable mass; 14 patients with small cysts required no treatment. Nine patients were operated upon, while 3 patients with large cysts were treated exclusively by ultrasonically guided drainage. Further, ultrasonically guided drainage was successful in two patients with recurrences after surgical treatment. Patients with small asymptomatic cysts of the liver, incidentally diagnosed should be left without treatment. Ultrasonically guided puncture is advocated as the first treatment in patients with large symptomatic cysts.

Adult↗
PubMed1982

Ultrasonic localization of the porta hepatis prior to percutaneous transhepatic cholangiography.

Sixtyfour jaundiced patients were randomly allocated to have fine needle PTC performed with or without prior ultrasonographical localization of the porta hepatis. The general success rate was 97% and complications occurred in two patients (3%). Ultrasonography prior to PTC did not significantly reduce the number of needle passes in the liver parenchyma, the failure rate or the number of complications. Ultrasonic scanning, however, should precede PTC to disclose patients with obstructive jaundice and reveal hepatic and perihepatic abnormalities.

Adult↗
PubMed1982

Ultrasonography, 99mTc-DIDA cholescintigraphy, and infusion tomography in the diagnosis of acute cholecystitis.

Ultrasonography, 99mTc-DIDA cholescintigraphy, and infusion tomography of the gallbladder were compared in a prospective study comprising 45 consecutive patients clinically suspected of having acute cholecystitis. The diagnosis of acute cholecystitis was established or excluded by operation in 35 patients, by oral cholecystography in 5, and by intravenous cholangiography in 5. The predictive values of a positive and a negative test were 100% and 83%, respectively, by ultrasonography and 98% and 88% by cholescintigraphy. Corresponding values for infusion tomography were 87% and 33%. The results suggest that in patients suspected of having acute cholecystitis, 99mTc-DIDA cholescintigraphy and ultrasonography provide a rapid and reliable diagnosis.

Acute Disease↗
PubMed1981

Dynamic sonography in the evaluation of jaundice.

The value of dynamic sonography as a screening procedure in 84 jaundiced patients was examined and compared with the clinical evaluation of a blind prospective study. The predictive value of the sonographic diagnosis of obstruction was 97% and 84% in nonobstruction. The corresponding values of the clinical distinction were 87% and 92% respectively. The level of obstruction was demonstrated in 95% and the cause of obstruction was diagnosed in 68%. When the cause of jaundice is uncertain or obstruction is suspected clinically, dynamic sonography can offer high diagnostic accuracy and guidance for invasive investigations.

Adult↗