Biomedical subjects

S Harbottle

Publications and source records attributed to S Harbottle.

2 recordsLinked to original sources

PubMed1986

Surface alterations in dialysis roller pump inserts: a scanning electron microscopy study.

Scanning electron microscopy has been used in a study of particle spalling from silicone and PVC elastomer inserts of dialysis roller pumps. In an experimental circuit using Isoton II, pump occlusion, pressure, pump revolutions and temperature were monitored. Scanning electron microscopy was performed on inserts exposed to 1-10 h of pumping using Silastic (medical grade) and a Watson-Marlow MHRE pump, with PVC and Pivipol, a polyurethane coated PVC (Bellco) using a Bellco BL705N pump. Changes included longitudinal splits (single and multiple), superficial cracks (random and orientated), deformations of normal surface pattern, holes, craters and detaching particles. There was an increase in these abnormalities with time for all types of pump insert, the changes being most marked for the Silastic/Watson-Marlow pump combination and least prevalent with the PVC/Bellco pump combination.

Humans↗

PubMed1986

Particle spallation induced by blood pumps in hemodialysis tubing sets.

The repeated flexion and compression of pump segments by the rollers of peristaltic pumps results in cracking and abrasion of the inner surfaces of the pump segment, leading to shedding of particles into the extracorporeal circuit. A series of studies to assess the rate of particle release from silicone rubber, polyvinyl chloride (PVC), and Pivipol, a coextruded polyurethane-coated PVC tubing, when these materials were used with blood pumps of the type found in hemodialysis units, was undertaken. The studies show that with all tubing/pump combinations there is an overall increase in the total number of particles released, but an analysis of the particle size distribution indicates that the majority of the particles are less than 16 micron in diameter. The rate of increase may be reduced, however, by decreasing the occlusion pressure.

Analysis of Variance↗