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Biomedical subjects

S Hedenstedt

Publications and source records attributed to S Hedenstedt.

At least 19 recordsLinked to original sources
PubMed1980

Selective proximal vagotomy without drainage in the treatment of duodenal ulcer. The results after a standardization of the surgical technique. A five-year follow-up.

Selective proximal vagotomy without polyoroplasty has been shown to be a difficult operation to perform and some investigator have got a rather high frequency of recurrencies and operative complications. In an attempt to reduce the surgical failures a standardization of the operation has been undertaken. In the present material the long term results of a material operated upon with stardardized technique has been estimated. The operation resulted in a high reduction of the ability to secret acid. 90% of the patients had almost no side effects of the operation and 4.4% got a relapse. The relapses developed in patients with a negative postoperative insulin test. The prognostic value of the insulin test seems therefore doubtful.

Adult↗
PubMed1975

Clinical, secretory and motor effects of selective proximal vagotomy. A three-year follow-up.

Sixty-three patients with duodenal ulcer were operated upon with selective proximal vagotomy (SPV). In 34 patients the vagotomy was combined with a pyloroplasty (PP). Before and after operation the acid secretion was investigated after Histalog (50 mg) stimulation. Insulin tests were performed 4-6 weeks, 1 year, and 3 years after operation. One and 3 years after operation ESR, Hb, SeFe, Protein, Albumin, Calcium, and Alkaline phosphatases were determined. One patient developed gastric retention and 3 got relapses during the first year. At reoperation, overlooked vagal branches in the region of the cardia were found. Five patients developed a minor anemia and 2 sideropenia, which is less than after truncal vagotomy and PP. The operation caused a highly significant reduction in acid output after Histalog stimulation. The postoperative insulin test was graded according to Bachrach: 49 were complete, 12 extensive but incomplete, and 2 incomplete. During the second hour after stimulation a probably significant increase was noted in the acid output between the postoperative and the one-year investigation. Between the one- and the three-years tests a significant increase was found during the first hour after insulin stimulation and a probably significant increase during the second hour. The gastric emptying of a composite fluid test meal was significantly faster after operation than before in patients where the insulin stimulation did not give rise to any acid production.

Adolescent↗