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Biomedical subjects

S Herbst

Publications and source records attributed to S Herbst.

At least 19 recordsLinked to original sources
PubMed2001

GIS-based analysis of drinking-water supply structures: a module for microbial risk assessment.

Water-related infections constitute an important health impact world-wide. A set of tools serving for Microbial Risk Assessment (MRA) of waterborne diseases should comprise the entire drinking-water management system and take into account the Hazard Analysis and Critical Control Point (HACCP) concept which provides specific Critical Control Points (CCPs) reflecting each step of drinking-water provision. A Geographical Information System (GIS) study concerning water-supply structure (WSS) was conducted in the Rhein-Berg District (North Rhine-Westphalia, Germany). As a result, suitability of the existing water databases HYGRIS (hydrological basis geo-information system) and TEIS (drinking-water recording and information system) for the development of a WSS-GIS module could be demonstrated. Spatial patterns within the integrated raw and drinking-water data can easily be uncovered by GIS-specific options. The application of WSS-GIS allows a rapid visualization and analysis of drinking-water supply structure and offers huge advantages concerning microbial monitoring of raw and drinking water as well as recognition and investigation of incidents and outbreaks. Increasing requests regarding health protection and health reporting, demands for a better outbreak management and water-related health impacts of global climate change are major challenges of future water management to be tackled with methods including spatial analysis. GIS is assumed to be a very useful tool to meet these requirements.

Environmental Monitoring↗
PubMed1996

Application of ambulatory infusion devices in infusional cancer chemotherapy: a model for nursing management.

Optimal support of the patient receiving infusional cancer chemotherapy (ICC) in the home setting is partially dependent on the provision of an infusional device that offers minimal complexity and maximal reliability and safety. The selection of the appropriate device is vital to positive patient outcomes and to the comfort level of both patient and care providers. This article presents issues and considerations in the selection of infusion devices and the nursing role in the management of patients utilizing such devices. Aspects of nursing management are presented from the perspective of The Cancer Center of Boston (TCC) model.

Ambulatory Care↗
PubMed1979

Continuous intravenous arabinosyl cytosine infusions delivered by a new portable infusion system.

Eighty-six patients with acute leukemia were given 116 continuous intravenous arabinosyl cytosine (Ara-C) infusions (for 24 to 432 hours) with a new portable infusion device. The infusor is powered by interchangeable elastomeric 25 ml balloon reservoirs loaded from standard syringes. The reservoir contents are discharged at nearly constant pressure through an adjustable resistance element, thereby providing flow rates from 0.4 to 2.0 ml/hour. Serum levels of labeled Ara-C delivered by the infusor were found to achieve steady-state therapeutic levels within 24 hours. The average-flow-rate-to-indicator-setting ratio determined for each infusion via scalp vein needles was 0.9 +/- 0.2. Delivery through catheters was more reliable and an average-flow-rate-to-indicator-setting ratio of 0.1 +/- 0.1 was observed. The therapeutic effectiveness of Ara-C in combination with other agents was not compromised by this delivery system. Eleven of 14 patients who received all their induction Ara-C through the infusor achieved complete remission.

Acute Disease↗
PubMed1977

[Sterilization by partial resection of the oviducts via bipolar electrocoagulation (author's transl)].

A total of 2,357 sterilizations via bipolar coagulation was effected at the University Clinics of Gynecology at Basel and Tübingen since 1972 and 1975 respectively. Of these, 2,143 were effected via laparoscopy. The following complications occurred which required laparotomy: in two cases, hemorrhages from the abdominal cavity as a result of the second puncture, in one case from the mesosalpinx, and, as a late complication, two extrauterine pregnancies. The method failed in the case of the two extrauterine pregnancies and possibly also in the case of two doubtful intrauterine pregnancies (0.8--1.7 per thousand). Today this surgical measure is being performed in Tübingen exclusively by the single-puncture technique an increasingly under local anesthesia. The advantages of the method are an accurately determinable coagulation zone, sparing of the mesosalpinx, low incidence of complications, absence of life-threatening incidents, and low failure quota.

Anesthesia, Local↗