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Biomedical subjects

S Herszenson

Publications and source records attributed to S Herszenson.

5 recordsLinked to original sources
PubMed1982

The involuting lichenoid plaque.

Progressive involution and subsequent regression of a plaque that showed the characteristic histologic findings of solitary lichen planus-like keratosis were observed in five patients. In each lesion, involution took place during a four- to eight-week period. In four patients, the lesion arose in a preexisting pigmented macule. Evolution into a plaque-like lesion coincided with the development of the inflammatory process. Origin from a preexisting lesion suggests that the lichenoid plaque is not an independent entity but a stage in the involution of the preexisting pigmented macule. The lichenoid inflammatory process resembles a delayed hypersensitivity reaction and seems to represent a cell-mediated rejection reaction.

Female↗
PubMed1981

Vascular response in halo of recent halo nevus.

The depigmented halo of a recently acquired halo nevus showed prominent erythema. Microscopic examination of a specimen from the halo showed dilatation of the dermal blood vessels, thickening of the vessel walls, and swelling of the endothelial cells; cellular infiltration was totally absent. Direct immunofluorescent studies on skin from the halo failed to show vessel, basement membrane, or intercellular fluorescence with IgG, IgM, IgA, C3, and fibrin. We conclude that the erythema in the skin of the depigmented halo is the result of dilated dermal blood vessels and that the mechanism of vascular dilatation is not associated with direct infiltration by inflammatory cells nor with immune complex formation. Erythema in the skin of the depigmented halo has not, to our knowledge, been studied previously.

Adult↗
PubMed1980

Childhood pemphigus foliaceus. Report of a case.

A case is reported of a 4-year-old black boy with pemphigus foliaceus. The patient is unusual because of age, sex, race, and distribution of lesions, Confirmation of diagnosis was made by both routine histopathology and direct immunofluorescence microscopy. The patient responded rapidly to prednisone therapy.

Black People↗