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Biomedical subjects

S I Belykh

Publications and source records attributed to S I Belykh.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Connective elements for internal organs made of biocompatible polymers].

The paper provides technical characteristics of ESB biocompatible polymer connective elements (of polymethacrylate butyl) for internal organs. Problems of the changes of their physico-mechanical properties during experiments in model environments were discussed. Also results of medical and experimental studies of connective elements on animals, and of their biodestruction, were analyzed. Findings which could be used in clinical use of the connective elements in operating parenchymatous organs and in stomatology and traumatology are shown. On the basis of results obtained after 128 operations it was found that use of ESB connective elements ensures high reliability of haemostasis, and prevents unsealing, both physical and biological, of internal sutures and rules out any adhesion. Moreover it diminishes, in some cases even rules out, the possibility of post-operative complications.

Animals↗
PubMed1987

[Endoprosthesis of the larynx using polymer materials].

An endoprosthesis for the formation of the larynx lumen in the postoperative period has been developed. The possibility of using the endoprosthesis was proved experimentally. An experience with 112 operations on the larynx with this prosthesis for the prevention of postoperative complications and earlier social rehabilitation of such patients allowed it to be recommended for clinical practice.

Animals↗
PubMedDate not supplied

Chemical and physicomechanical aspects of biocompatible orthopaedic polymer (BOP) in bone surgery.

The properties of biocompatible orthopaedic polymer developed as an alternative to the metallic materials used in reconstructive bone surgery are discussed. Experiments were conducted to enhance the mechanical characteristics of the polymer by incorporation of various fibres. The result was a super biocompatible orthopaedic polymer which could be a valuable alternative to intra-medullary long bone metallic rods, whilst normal biocompatible orthopaedic polymer is currently used for bone filling and reconstructive surgery.

Biocompatible Materials↗
PubMedDate not supplied

[Strategic problems in counteracting the spread of HIV infection in the Altai Territory].

The Altai Territory belongs at present to regions with the insignificant level of the spread of HIV infection. By December 1, 1999, the Altai Territory had 31 registered cases of HIV infection, which constituted 1.33 per 10,000 of the population (the corresponding figure for the whole of Russia being 14.92). But the situation with HIV/AIDS showed the general tendency to the development of the epidemic of HIV infection due to steady growth and the wide involvement of injecting drug users in the epidemic process. Before 1999 all cases of HIV infection registered in the Altai Territory were imported. Out of 31 HIV infected persons detected in the territory, 18 were injecting drug users. In 1999 local foci of HIV infection were formed among drug users in two big cities of the Altai Territory, which was indicative of the gradual transition of HIV infection from the phase of the registration of individual cases to the phase of the formation of local foci among some groups of the population.

Adolescent↗
PubMedDate not supplied

[Molecular and epidemiological characterization of HIV-infection in the Altai Territory].

The genetic analysis of the variants of HIV, type 1, circulating in the Altai Territory was made. The results obtained with the use of the serological analysis and the method of the comparative evaluation of the electrophoretic mobility of heteroduplexes demonstrated that almost all analyzed samples (98.3%) belonged to subtype A. Genetic differences between these viruses did not exceed 9.20%. Moreover, 86.8% of them contained mutation V771 in the protease-coding area. Thus, HIV of subtype A, characteristic of CIS countries and containing mutation V771, may be regarded as the dominating viruses in the Altai Territory and not the viruses of subtypes B, C or A/E, typical of comparatively less remote China.

HIV Infections↗
PubMedDate not supplied

[Enteroplasty in bladder tumors].

A total of 429 patients with urinary tumors have been operated on in the past 10 years, 80 of them have been undergone cystectomy. Intestinal plasty of the urinary bladder was performed in 38 patients. These one-stage operations in 15 patients yielded a high postoperative mortality rate (33.3%). Two-stage surgeries in 23 patients largely reduced mortality (8.9%). The authors provide recommendations how to conduct the two-stage surgery and limited indications for one-stage interventions.

Adult↗
PubMedDate not supplied

[Reparative osteogenesis in the implantation of different modifications of a biocompatible polymer].

Presents a histological picture of the time course of repair osteogenesis in replacement of bone tissue defects with implants made of 4 various copolymers of N-vinylpyrrolidone. Demonstrates excellent morphofunctional qualities of newly formed tissue substrate and its maturity in replacement of bone tissue defects with implants of N-vinylpyrrolidone with butylmethacrylate.

Animals↗
PubMedDate not supplied

[Local preventive antibacterial therapy with polymer biocompatible combination].

The paper provides data on the properties of the powdery antimicrobial absorbent Ambipor and the procedure of its use in the prevention of postoperative suppuration, which consists in application of the powder to the wound surface with a broken layer just before wound suture. It shows that a single application of Ambipor to wound suture. It shows that a single application of Ambipor to wound tissues at the end of an operation ensures high paravulnar tissue antibiotic concentrations which are many times higher those used in conventional antibacterial therapy. Implantation of Ambipor to operative wound tissue at the end of an operation aids to reduce the extent microbial dissemination by more than 100-1000 times, to accelerate reparative processes, stimulate early fibroplast activation, fibrillogenesis, scarring tissue maturation. Topical antibacterial therapy with the developed formulations is an effective tool in preventing postoperative wound complications. Its application to clinical practice enables the incidence of complications to be decreased by more than 4.5 times higher than those in the controls.

Administration, Topical↗
PubMedDate not supplied

[Use of biocompatible soluble polymers in reconstructive surgery].

The paper provides the functional characteristics and results of clinical application of implants based on N-vinylpyrrolidone-butylmethacrylate copolymer to eliminate mandibular bone defect. The implants are indicated to ensure reliable fixation and promote the formation of a valuable osseous regenerate due to their capacity to self-resolve and osteoconductivity. The application of the N-vinylpyrrolidone-butylmethacrylate copolymer-based implants substantially widens the scope of reconstructive surgery.

Biocompatible Materials↗
PubMedDate not supplied

[BOP-polymer implants for fixation of tubular bones and replacement of osseous tissue defects].

The paper provides the functional characteristics of and clinical findings of the employment of 4 pins for osteosynthesis from biocompatible polymers and shows that the pins ensure reliable fixation of bone fragments and due to their ability to resolve in the body they require no repeated operations for their extraction. The application of the polymer pins substantially widens the scopes for reconstructive operations, enables additional fixation to eliminate rotor mobility, additional fixation of bone fragments, allowing for combined osteosynthesis in fractures of the upper and lower thirds of bones. The employment of antimicrobial pins allows one to prevent postoperative suppurations in open fractures and to treat osteomyelitis. The developed material to fill bone defects with PPV ensures a rapid filling of osseous cavilities with its intrinsic osseous regenerates, recovery of normal osseous tissue in Perthes' disease, and fixation of endoprostheses. The author presents a procedure for applying a kit for replacement of skull defects and indicates that the material substitutes defects of various outlines and rapidly restores the strength characteristics of the skull.

Bone Diseases↗