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Biomedical subjects

S I Chun

Publications and source records attributed to S I Chun.

At least 19 recordsLinked to original sources
PubMed2000

Solitary sclerotic fibroma of the skin: degenerated sclerotic change of inflammatory conditions, especially folliculitis.

Two cases showing changes of sclerotic fibroma developed in association with an inflammatory process, especially folliculitis. The lesion in the first case showed a well-circumscribed, nonencapsulated nodule in the dermis, which consisted of a perifollicular fibrotic area and a peripheral sclerotic area. In addition to the usual findings of sclerotic fibroma, spindle cells were heavily infiltrated in a storiform and fascicular pattern around the degenerated hair follicle, suggestive of dermatofibroma. The lesion in the second case showed the typical findings of sclerotic fibroma in association with folliculitis and hair follicle remnants. Our observations suggest that solitary sclerotic fibroma of the skin may be a degenerated or sclerotic end stage of other fibrous conditions, such as dermatofibroma, and that it may be induced by inflammation, especially folliculitis.

Adult↗
PubMed2000

A case of primary cutaneous actinomycosis.

Primary cutaneous actinomycosis is very uncommon because of the exclusively endogenous habitat of the organism. We report a case of primary cutaneous actinomycosis characterized by histopathological "sulfur granules". The patient had a well-defined subcutaneous nodule on the left thigh without any other lesion and was treated with surgical excision and subsequent oral ampicillin for six weeks. There has been no recurrence during a 1-year period of follow-up.

Actinomycosis↗
PubMed1999

[One hundred years history of surgery in Korea].

Introduction of western surgery into Korea is closely related to the introduction of western medicine itself into Korea. In December 4th, 1884 Allen, who came to Korea as a Missionary Doctor of North Presbyterian Church of America, had a chance to treat a patient with severe stab wounds. The patient was a nephew of Queen Myungsung. The patient, Min Young Ik was recovered completely. These happenings led to the establishment of 'Kwangheywon (renamed to Jejoongwon 2 weeks later)', the first westernized hospital in Korea. With the great financial aids from Severance family, Jejoongwon developed into Severance Hospital and Medical School in 1904, and greatly contributed to education of Surgery for Korean medical students. Meanwhile Korean Government established the Medical School and Hospital to train Korean Doctors in 1899. But the original intentions became to be impaired by occupation of Korea by Japan in 1910. As a colony, many Japanese Surgeons came to Korea as professors of Kyungsung Medical College, and gave only few chances for Koreans to become a professor. On the contrary, several surgeons became professors in the private, missionary 'Severance Union Medical College'. After liberation from Japanese occupation in 1945, American medical system was introduced into Korea, and many surgeons had a chance to be trained in America. There was great advancements in the field of surgery, especially of neurosurgery, during a tragic Korean War. With the restoration of economy after the 1960s, surgery in Korea continued to develop toward an independent and consolidated fields of medicine.

Colonialism↗
PubMed1998

A case of loiasis.

The prevalence of Loa loa infections in non-endemic areas such as Korea is very low, even though it is quite common in the endemic regions of West and Central Africa. We describe a patient who presented with temporary localized edema (classical Calabar swellings) after travelling to Cameroon and in whom the diagnosis of loiasis was made by ELISA. This is the second reported case of loiasis in Korea. As international travel is becoming more frequent, Loa loa infection should be considered in the differential diagnosis for patients with eosinophilia and Calabar swellings in Korea.

Adult↗
PubMed1997

Interlimb interaction and stabilization of contralateral leg in isokinetic knee evaluation.

OBJECTIVE: To determine if peak torque (PT) production during isokinetic knee testing is affected by the stabilization and movement patterns of the contralateral leg. DESIGN: Repeated measure design. INTERVENTION AND MAIN OUTCOME MEASURE: Thirty subjects participated in comparing the force outputs in relation to the movement pattern of both legs. Another group of 45 subjects volunteered to perform five maximal isokinetic extension-flexion contractions in each of three different knee testing conditions: (1) without stabilization of the contralateral leg; (2) with a bar in front of the ankle joint of the contralateral leg; (3) with the contralateral leg strapped just above the level of the malleoli and the muscles of that leg induced reciprocally to perform isometric contractions with respect to the testing leg. PT was used to compare the strength of three different conditions. RESULTS: Significantly greater PT was measured when the contralateral leg of the subject was fixed and induced to contract reciprocally. CONCLUSION: More rigorous standardization of isokinetic strength testing procedures is needed due to differences in PT production of knee muscles according to the stabilization and movement pattern of the contralateral leg.

Adult↗
PubMed1995

Acquired cutis laxa associated with chronic urticaria.

A 31-year-old man had cutis laxa after an urticarial eruption. He had no systemic manifestations. In urticarial lesions, elastolysis occurred only within the inflammatory infiltrate of neutrophils around the vessels and between the collagen bundles. In lax skin, elastolysis occurred throughout the entire dermis. Electron microscopic study showed a markedly decreased number of elastic fibers, with elastolysis most predominant near the inflammatory cells. These findings suggest that the neutrophil plays a significant role in the destruction of elastic fibers and subsequent development of cutis laxa.

Adult↗
PubMed1995

Exercise effect of modified contralateral stabilization bar during one-legged isokinetic exercise.

We compared the electrical activities recorded from the muscles of the unexercised leg with changing the position of the contralateral stabilization bar to determine whether the degree of muscle contraction was influenced by the position of the bar during one-legged isokinetic exercise using an isokinetic dynamometer. The root mean square (RMS) values recorded from the medial hamstring sites of the unexercised legs showed a significantly higher value when the bar was located behind and on both in front of and behind the unexercised leg during one-legged extension exercise. Results from the isokinetic knee flexion exercise test indicated that a significantly greater RMS value was recorded from the vastus lateralis sites when the bar was located in front of and on both sides of the unexercised leg. During one-legged isokinetic extension-flexion exercise, the mean values of RMS voltage were greater when the bar was positioned in front of and on both sides of the unexercised leg in the vastus lateralis site. At the medial hamstring site, a greater value was noticed when the bar was located behind or on both sides.

Adult↗
PubMed1995

Disseminated epidermolytic acanthoma with disseminated superficial porokeratosis and verruca vulgaris in an immunosuppressed patient.

A 40-year-old man who had received long term immunosuppressive treatment for 14 years following kidney transplantation developed multiple skin lesions on both antecubital fossae, scalp, and both lower extremities. Histopathologic findings from three skin regions revealed characteristic features of epidermolytic hyperkeratosis, verruca vulgaris, and disseminated superficial porokeratosis, respectively. Although immunocompromised individuals may demonstrate verruca vulgaris or porokeratosis, disseminated epidermolytic acanthoma (DEA) has not been reported to be associated with immunosuppressed status. We suggest that immunosuppression may play a role in the pathogenesis of DEA, as shown in our case.

Adult↗
PubMed1995

Correlation of spinal mobility with the severity of chronic lower back pain.

The purpose of this study is to show the correlation between the range of spinal motion and the severity of chronic lower back pain. The subjects of this study were 40 female patients with chronic lower back pain over a 6 months' duration. The range of spinal and hip joint motion was measured with a electrogoniometer, and the severity of back pain was evaluated with the Rolland's score and Pollard's pain disability index. Results were as follows. There was a correlation between the severity of pain and the range of lumbar lateral flexion, rotation, and extension (p < 0.05). Age, height, weight and body mass index had no correlation with the range of spinal motion. These results suggest that the range of lumbar spinal motion can be used as an objective measure for the evaluation of classifying chronic lower back pain patients and for planning and following their treatment.

Adult↗
PubMed1994

Membranous lipodystrophy: secondary type.

BACKGROUND: A peculiar type of fat necrosis was noted in some patients with various skin diseases. OBJECTIVE: We attempted to develop a classification of membranous lipodystrophy combining the results of our study and a review of other articles. METHODS: Five cases of skin diseases with membranous lipodystrophy were studied and their clinical and histopathologic features were analyzed. Previous reports of similar findings were reviewed. RESULTS: Membranous lipodystrophic changes were noted in morphea profunda, lupus panniculitis, and factitial ulcer. Microcysts were formed by the coalescence of the destroyed fat cells and were lined by amorphous, eosinophilic material. Some of the linings had a crenelated appearance. Microgranules were found in the histiocytes and in the hyalinized collagen stroma. The linings and microgranules stained positively with periodic acid-Schiff, were resistant to diastase, and also stained with Sudan black B. CONCLUSION: We propose the use of the term secondary membranous lipodystrophy to describe the local subcutaneous membranous lipodystrophic change that occurs as a result of other skin diseases, in contrast to primary idiopathic membranous lipodystrophy, which occurs without any antecedent factors.

Adipose Tissue↗
PubMed1994

An unusual form of skin tuberculosis following B.C.G. vaccination.

A 25-year-old female has had brown to erythematous telangiectatic patches and grouped papules on her face, neck, arm, and trunk since childhood following B.C.G. vaccination. Histopathologically, the lesions consisted of hyperkeratosis, slight acanthosis, tuberculoid granulomas with some Langerhans type giant cells in the mid-dermis. Although various forms of cutaneous tuberculosis after B.C.G. vaccination have been reported, it was difficult for us to assign the patient's skin lesion to any specific disease entity. Remission of her cutaneous lesions occurred clinically and histopathologically after treatment with isoniazid and rifampin.

Adult↗
PubMed1994

Sympathetic skin response recorded by 4 channel recording system.

The main purpose of this article is to determine a method of supporting the sympathetic skin response (SSR) as a sensitive clinical test. Using a non-invasive technique the SSRs are simultaneously recorded by 4 channel EMG machine. Thirty adults (10 women and 20 men, aged 19 to 46 years), normal and healthy, participated in this experiment. Not only did the latencies recorded on both palms respond faster than those on both soles, but the amplitudes measured on the palms were also higher. From these observations, one is bound to conclude that the SSR is not a segmental response but a long systemic response. More than two channel EMG recordings are desirable to see whether or not there is a lesion in any part of the SSR's pathway. Comparing the SSRs made both on the palms and soles simultaneously is recommendable in order to increase the its sensitivity.

Adolescent↗
PubMed1994

The basal electrical skin resistance of acupuncture points in normal subjects.

The inhibitory component of the skin against given electrical current, also called as the electrical skin resistance, is subject to change in response to many factors, especially pain. In order to find out more definite relationship between pain and skin resistance, one should make measurement in the state devoid of any external disturbing stimuli to get the "basal skin resistance (BSR)", which is known to be different from point to point on body surface. Also, the "active points" have more consistent BSR characters than other points and most of them share same locations with "acupuncture points" which is easy to localize accurately and repeatedly in normal subject. Therefore, the comparison of BSR of certain acupuncture points of normal subject and pain-suffering subjects is expected to be able to figure out any pain-induced BSR changes. Our measurement at 16 acupuncture points (asymmetrical 8 pairs) of 10 normal subjects showed inconsistently asymmetrical distribution of the BSR values with significant order among themselves including left SP (spleen)-6 at their lowest position, but neither the measuring system itself nor any of the 16 points was statistically reliable enough for diagnostic purposes. So the measuring device needs to be improved with after evolution, and more acupuncture points need to be explored to complete our pain-related BSR map. In addition, the meaning of the above BSR distribution pattern is waiting to be explained through such efforts.

Acupuncture Points↗
PubMed1993

Pudendal somatosensory evoked potential and bulbocavernosus reflex testing in erectile dysfunction.

Pudenal somatosensory evoked potential (PSEP) and bulbocavernosus reflex (BCR) testing have been reported to be useful in the evaluation of erectile dysfunction and neurogenic bladder. 461 patients with sexual dysfunction were studied to determine the usefulness of the above tests. Abnormality of PSEP was found significantly in upper motor neuron (UMN) type spinal cord patients and average prolonged P1 latency was 47.4 +/- 9.8 msec. Lower motor neuron (LMN) type spinal cord patients revealed great abnormality in BCR latency with an average value of 44.9 +/- 14.5 msec on the right and 44.2 +/- 15.6 msec on the left. Additionally significant differences were obtained in patients with diabetes mellitus, pelvic trauma and spinal cord lesion of the UMN type in the study of PSEP. There was also a significant difference in the patients with diabetes mellitus, pelvic trauma and spinal cord lesion of the LMN type in the BCR study. The findings of our study suggest that PSEP together with BCR study is useful in assessing the integrity of the sacral reflex arc and the central afferent pathway, in differentiating the lesion site and in providing basic data for the management plan in sexual rehabilitation. Furthermore, because erection is under the influence of both the somatic and autonomic nervous system, BCR study and PSEP combined with currently studied electrical activity of the corpus cavernosum would provide a more accurate evaluation of the neurogenic erectile dysfunction patients.

Adult↗
PubMed1992

Kimura's disease and angiolymphoid hyperplasia with eosinophilia: clinical and histopathologic differences.

BACKGROUND: There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE). OBJECTIVE: We describe the clinical and histopathologic differences between the two diseases. METHODS: We reviewed clinical findings and histopathologic changes in two cases of Kimura's disease and three cases of ALHE. RESULTS: Kimura's disease shows typical lymphoid follicles. It is associated with lymphadenopathy and is always accompanied by peripheral eosinophilia. ALHE shows typical changes in endothelial cells. It is characterized by superficial papules or nodules with no lymphadenopathy and is less frequently accompanied by peripheral eosinophilia. CONCLUSION: Kimura's disease and ALHE are separate entities.

Adrenal Cortex Hormones↗
PubMed1992

Linear morphea with secondary cutaneous mucinosis.

Secondary mucinosis is a common finding in connective tissue diseases, especially in lupus erythematosus and dermatomyositis, but is seen only rarely in morphea. We report the case of a 9-year-old boy who presented with linearly arranged, flesh-colored to erythematous, indurated, very tender plaques on his right arm. He had similar lesions on his midchest and upper back. Histopathology revealed the characteristic findings of morphea and mucin deposition between thickened collagen bundles. This is an unusual case of linear morphea with hyaluronic acid deposition.

Child↗
PubMed1992

Congenital self-healing reticulohistiocytosis--report of a case of the solitary type and review of the literature.

A 2-month-old female infant presented with a single hemorrhagic crusted papule on the chin present since birth. No visceral involvement could be demonstrated. The lesion involuted spontaneously with scarring in 3 months. Mononuclear cells in the cutaneous infiltrate were Langerhans cells with typical Birbeck granules which positively stained with S-100 protein. This case is the solitary type of congenital self-healing reticulohistiocytosis.

Female↗