[Nervous system damage caused by solvents].
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Brain Damage, Chronic↗
Biomedical subjects
S I Fandrem
Publications and source records attributed to S I Fandrem.
[When does the occupational environment cause lung disease?].
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Air Pollutants, Occupational↗
Incidence of cancer among workers in a Norwegian nitrate fertiliser plant.
The incidence of cancer among 2023 male fertiliser workers has been investigated in a historical cohort study. Workers who had been employed for more than one year in work with possible exposure to dust containing nitrate between 1945 and 1979 were included. An individual cumulated exposure to dust expressed in level-years was calculated for each participant. The cohort was followed up from 1953 to the end of 1988, and the incidence of cancer was compared with the national rates. There were 467 deaths v 504.8 expected (standardised mortality ratio (SMR) = 0.93), and 185 cases of cancer v 195.5 expected (standardised incidence ratio (SIR) = 0.95). Thirty cases of lung cancer were found v 27.5 expected (SIR = 1.09). No overall excess of gastric cancer was found (15 cases v 17.0 expected; SIR = 0.89). No association was found between cumulated exposure to nitrate and gastric cancer, and there was no association between duration of employment or time since first employment and incidence of gastric cancer.
Cohort Studies↗
Birth weight and environmental pollution in the county of Telemark, Norway.
The possible effect of environmental pollution on fetal growth was examined in 3,231 consecutively liveborn single infants (>/=37 weeks' gestation) of Caucasian parents born between 1986 and 1988. The parents lived in an industrial area or in less polluted urban and rural residential areas. Information about lifestyle, health, and work exposures was collected from the parents. A significantly lower arithmetic mean birth weight was observed for newborns in the industrial residential area (3,517 g, SD, 482), compared with the urban (3,592 g, SD 495) and rural (3,618 g, SD 517) areas (P < 0.05). Even controlling for gestational age, sex, parity, maternal smoking habits, and social class, residential area still had a significant effect on birth weight. Among other factors examined, only maternal psychological stress at work had a significant effect on birth weight. If the observed association reflects a causal relationship, birth weight may represent a potential outcome parameter for surveillance of effects on humans of environmental exposures.
Adult↗