[Prognosis of accumulative characteristics of chemical substances based on using acute experimental data].
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Biomedical subjects
Publications and source records attributed to S I Goncharov.
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Analysis of data on chronic toxicity of chemical elements and their metabolism in the human organism show the actual equality of the maximum ineffective dose and the daily dose. Authors considered, that the 2-fold excess of actual dose is not harmful for the human health.
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The analysis of 3 chronic experiments on white rats pertaining to the study of the combined effect of noise at 85 and 95 dBA and aerosols containing manganese, chromium, nickel oxides and SiO2 showed that there were noted the effects caused by their combined impact. The shifts were clearly marked in the state of the endocrine and cardiovascular systems.
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