Biomedical subjects

S I Preĭgel'

Publications and source records attributed to S I Preĭgel'.

3 recordsLinked to original sources

PubMed1990

[Evolution of recombination in "host-parasite" systems. Multilocus models].

Evolution of the recombination system caused by antagonistic species interactions (host and parasite, for example) was studied. The genetic structure of host population as well as that of parasite is explicitly present in our models. The selection intensity depends on host's resistance and parasite's virulence, both controlled by polygenic systems. The rec-system dynamics was numerically studied using the genetic operators method. It is shown that high-recombination alleles of the rec-modificator can have a short-term selective advantage in both interacting populations simultaneously.

Animals↗

PubMed1988

[Host-parasite interaction as a factor in the evolution of genetic recombination].

A model of the rec-system evolution determined by species interactions of the host-parasite type has been studied. In contrast to known formalizations, the genetic structure of both populations is clearly represented in our model, which makes it possible to set the mode of their interrelations in a more natural and biologically consistent way. The numerical analysis has revealed the situations, where nondecreasing oscillations of the linkage disequilibrium coefficient and, consequently, the selection favourable for higher recombination occur in a system. The evolutionary advantage of recombination has been demonstrated both in terms of population mean fitness and in the models with locus modifier of recombination.

Animals↗

PubMed1986

[Evolution of the dominance of rec-loci. A mathematical model].

The possibility of evolutionary explanation of dominance relations for alleles in selective-neutral rec-loci was explored by means of numerical experiments. It was shown that selection for two-loci fitness system causing the secondary (induced) selection for the rec-system, results in changing the allele frequency of the second-level modificator gene controlling the dominance relations in the rec-locus. The dominance of rec-allele, providing the favourable for the given conditions level of crossing-over between selected fitness loci, is established, due to these changes. It was found that the neutral dominance modificator can influence the dynamics of the whole system.

Animals↗