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Biomedical subjects

S I Rybakov

Publications and source records attributed to S I Rybakov.

At least 37 records · Page 2Linked to original sources
PubMed1997

[The first experiment in endoscopic surgery of the adrenal gland].

Laparoscopic adrenalectomy (LA) using transperitoneal lateral access was conducted in 56 patients from June 1994 to September 1996 yr. Unilateral adrenal gland tumor up to 8 cm in diameter was diagnosed in all the patients. All the patients are alive. LA is the method of choice in the patients with syndromes of Conn, Cushing, pheochromocytoma up to 8 cm in diameter. The LA conduction is not indicated if malignant or large (more than 8 cm in diameter) tumor was revealed.

Adrenal Gland Neoplasms↗
PubMed1993

[Surgical treatment of thyroid cancer].

A comparative analysis of the results of surgical treatment of 603 patients with malignant neoplasms of the thyroid gland before and after the accident at the Chernobyl atomic power station are presented. A very aggressive course of thyroid cancer in pediatric patients after the accident and the ensuing necessity to extend the indications for the performance of thyroidectomy with radical intervention on the regional lymph collectors are noted.

Accidents, Occupational↗
PubMed1993

[Morphofunctional characteristics of malignant thyroid gland tumors in children from various regions of the Ukraine, who have been victims of of the Chernobyl nuclear power plant accident].

Thyroid cancers in children from the affected areas of Ukraine were investigated by means of light (33 cases) and electron (20 cases) microscopy. Statistical data from 25 regions of Ukraine have been analyzed concerning thyroid cancer in patients aged up to 18 years for the period 1981-1990. There is an increase in the number of thyroid cancers in the children of Ukraine from 0.04-0.06 cases in the "pre-chernobyl" period to 0.23 cases per 10(5) children's population in 1990. In the children operated in the Clinic of the Institute of Endocrinology in 1990-1991, severe forms of thyroid lesions with metastases to the lymph nodes were noted. Histopathological studies show prevalence of different variants of papillary cancer with presence of follicular, solid, poorly differentiated areas. Ultrastructural analysis revealed polymorphism of tumour cells, various degrees of their differentiation and functional specialization that point to a mixed multicomponent nature of carcinomas.

Accidents↗
PubMed1989

[Bilateral tumors of the adrenal cortical substance].

The results of surgical treatment of 4 patients with bilateral tumors of the adrenal cortical substance are presented. In 1 patient, glucosteronoma was revealed, in 2--malignant glucoandrosteronoma, in 1--nonfunctioning cancer. The patients with functioning tumors were operated on in two stages with the interval of 3-4 weeks. In 1 patient, 3 years after removal of the left adrenal gland for cancer, a tumor of the contralateral gland was removed. In removing the nonfunctional tumors and aldosteronomas, the median laparotomy is expedient, in glucosteronomas and glucoandrosteronomas--extraperitoneal lumbotomic approach. All the patients are alive 1.5-8 years after the operation.

Adrenal Cortex↗
PubMed1981

[Use of cyproheptadine (Peritol) as a drug blocking corticotropin secretion in the treatment of Cushing's syndrome].

The results are presented of the combined drug treatment of 39 patients with Icenko-Cushing's disease, using steroidogenesis inhibitor chloditane (o.p-DDD) and corticotropin secretion blocker peritol (cyproheptadine). The control group of 40 patients, suffered from the above disease of the same severity, was treated with alone chloditane. In the control group the inhibition of the adrenocortical glucocorticoid activity by chloditane was accompanied by twofold increase in the blood plasma corticotropin level. The relapse was noted in 24 of 40 patients after 5 to 6 months. The inhibition of glucocorticoid activity did not induce corticotropin secretion activation in patients, treated with chloditane and peritol. At the delayed terms of the treatment course the basal level of plasmatic corticotropin continued to lower and averaged the subnormal values. Relapses of the disease were seen in only 8 of 39 patients. The combined chloditane-perikol treatment of Icenko-Cushing's disease is likely to be perspective.

Adrenocorticotropic Hormone↗