[A method for visualizing the thyroid gland in a system of coordinates].
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Biomedical subjects
Publications and source records attributed to S I Shevchenko.
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There was proposed the method of the thyroid gland (TG) visualization in the system of topographical coordinates and in the projection of the organ image on the anterior surface of neck. One hundred of patients with the TG pathology were examined with application of the method. There was noted the possibility of the TG visualization application in the system of coordinates for enhancement of the fine-needle aspirational biopsy quality and diagnostic examination in total.
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After operation for differentiated thyroid cancer, late assessment of the indices of cellular and humoral immunity was carried out in 37 patients ranging in age from 20 to 70 years. Control group included 38 healthy subjects of the similar age. In patients examined, increase in IgC content, absence of changes in IgA and IgM levels were noted. Relative content of B-lymphocytes was increased, total number of lymphocytes, T- and O-cells--significantly decreased.
Comparative assessment of the incidence of thyroid cancer in patients operated on for different thyroid diseases from 1980 to 1986 (2448 cases, group 1), and from 1987 to 1991 (1993 cases, group 2) was carried out. The increase in incidence of thyroid cancer in group 2 patients was noted as well, as that in incidence of cancer development among the other hyperplastic diseases of the thyroid gland, autoimmune thyroiditis in particular. The results obtained are indicative of the necessity for correction of the tactics of treatment and prophylactic follow-up of the patients with different forms of goiter.
It was determined that vasopressin has surface active properties and in nanomolic concentrations is capable to incorporate in lipoprotein monolayers which are formed from myocytes plasma membranes. By means of pH-metric and fluorescent analysis it was shown that vasopressin interacts with other membrane structures which have no specific receptors--phosphatidylcholinic liposomes and vesicles of sarcoplasmic reticulum of skeletal muscles causing increasing permeability of phospholipid bilayer for Ca2+ ions.
Examinations of smear impressions of postoperative biopsy specimens of the thyroid from adenoma patients have revealed among polygonal structures 1 to 20 spherical complexes (per micropreparation) consisting of relatively monomorphic follicular cells with intensively blue cytoplasm. The 'ball' size was 200-900 micron or more. Cellular composition, specific features of cellular structure, and the presence of spherical structures permit differentiating adenoma from goiter.
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Measures are designed which are undertaken to form a commission of health occupational experts (CHOE) at local and regional levels in connection with entitlement to disability among workers. Organizational issues are described on early identification and adequate treatment of diseases frequently leading to disability, on promoting motivation of health workers in the reduction of disability among workers, raising the quality of medical-labour examination, information supply of physicians and public health administrators of these problems. A recommendation is made of the necessity to place commissions and institutes of health occupational experts under the authority of ministries of public health of the USSR and union republics. Advisability of including the section devoted to disability issues into the progress report of curative and preventive institutions is emphasized.
Histological and immunomorphological study of the removed tumor and tissue of the thyroid was performed in 80 patients with differentiated thyroid cancer. Activation of immune reactions and immunocompetent cells was reported at the border with blastomatous process. The latter seems a factor contributing to a favorable run of differentiated thyroid cancer. The capacity of papillary and follicular cancer for multifocal growth limits indications for preserving surgery in such lesions.
Results of questionnaire survey of 275 physicians of major clinical specialties are provided in regard to 26 aspects of medical expertise. Information is provided which characterise physicians' knowledge of medical expertise provisions, the sources of this knowledge, the assessment of competence of this expert commission and of its director, ungrounded issue of sick lists, denial to identify factual disability, causes leading to this phenomenon and also ways of reducing the level of morbidity associated with temporary disability.
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In 67 patients at the age of from 23 to 69 years with different hyperplastic processes in the thyroid gland, the crystallographic investigation of the blood serum was carried out. The crystallograms varied depending on the character of a disease and functional state of the thyroid gland. Simplicity and informative value of the method permit to recommend it for wide use in the diagnosis of the thyroid gland diseases.
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