Biomedical subjects
Publications and source records attributed to S I Smirnov.
In anesthetized cats, electrical stimulation of the nucleus ambiguous elicited obvious changes in electrical activity of the pylorus: slow wave frequency decreased, spike potentials either appeared or disappeared depending on stomach wall functional state. Also, the electrical stimulation decelerated the heart rate and decreased arterial blood pressure.
In anesthetized cats, using method of the retrograde transport of the horseradish peroxidase and electrophysiological techniques, the dorsal motor nucleus neurons innervating upper portion of the duodenum were found. Maximal number of such neurons were found within 1.0 to 2.5 mm rostral to the obex. The effects of the neurons stimulation on the electrical activity of the duodenum smooth muscles were studied. Possible role of the dorsal motor nucleus neurons in realisation of gastro-duodenum motor reflexes is discussed.
Explore the source record for details and available documents.
In anesthetized cats, electrical stimulation of the dorsal motor nucleus area within 0(-)+1.5 mm rostral to ohex elicited obvious changes in electrical activity of pylorus. These findings suggest the existence of topically organized parasympathetic preganglionic cell groups within the DMN--"the stomach area", which exert excitatory and inhibitory influences on the stomach smooth muscles.
Extracellular recording of unit activity in the hypothalamic ventromedial nucleus performed in anesthetized and immobilized cats revealed the convergence of impulses of different modality on these neurons: induced by somatic, visceral and sound stimuli. The capacity of hypothalamic neurons (32%) to converge influences was increased after i.v. administration of 10 ml of 20% glucose solution. The firing rate was increased in 19% cases and the phase of the reaction was reversed in 23% neurons. The main type of the responses involved excitation in all the cells under study.
In anesthetized cats, extracellular recording of the unit activity revealed a considerable convergence of stimuli of different modality: no difference was observed between patterns of responses to visceral, somatic, visual or sound stimuli. I. v. infusion of glucose reduced the convergence ability in 26% of the neurons under study whereas increasing it in 9.7%. Firing rate was reduced in 24.3%. The data obtained emphasized the effect of glucose on functioning of the cells of lateral part of the hypothalamus.
The immobilized cats, the influences of 2nd somatosensory and temporal areas on responses of the caudate nucleus' neurons to stimulation of the tibial and splanchnic nerves, were studied. The majority of spontaneously active neurons responded to the cortical stimulation, mainly from the 2nd somatosensory area. Over half of the neurons revealed the "binareal" feature. The typical form of interaction of the cortical and sensory stimuli (with the 50-msec interval between the conditioning and the testing stimuli) was either partial or complete suppression of responses of the caudate neurons both to the somatic and to the visceral stimulation. The results of cortico-sensory interaction were independent of the nature and functional significance of the stimulated cortical areas.
Explore the source record for details and available documents.
Responses of spontaneously active neurons of the caudate nucleus to stimulation of the n. splanchnicus were extracellularly recorded in immobilized cats. Presence of multimodal neurons responding to stimulation of visceral, somatic and auditory sensory systems, was also determined in this structure. The data obtained suggest probable participation of the caudate nucleus' neurons in the mechanisms of interaction between visceral signals and somatic and auditory those.
In 81 patients with acute diffuse peritonitis and in 38 -- with local peritonitis the authors have studied dynamically changes in the content of total protein, protein fractions in the peripheral blood, and also in the albumin -- globulin coefficient. A comparative estimation of disorders in the blood protein content and issues of the disease, depending on the use of an anabolic steroid -- retabolyl, is given. Application of retabolyl in the complex therapy enabled to reduce the number of complications and lethal issues in operated patients with diffuse peritonitis.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.