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Biomedical subjects

S I Yum

Publications and source records attributed to S I Yum.

8 recordsLinked to original sources
PubMed1999

Capillary blood sampling for self-monitoring of blood glucose.

New and emerging capillary blood sampling technologies for self-monitoring of blood glucose (SMBG) are reviewed for their impact on factors pertaining to users such as pain, and from the standpoint of skin physiology and technical feasibility. Innovative blood sampling techniques based on lancets for skin penetration on nonfinger (alternate) sites such as the forearm seem to be virtually painless, convenient and cost effective as compared to other methods such as laser-based perforation of fingertips. Alternate site blood sampling with new lancet devices appears not only medically sound but also technically practical and user-friendly. It is anticipated that alternate site blood sampling techniques would improve compliance rate and, consequently, outcome of treatment for patients with diabetes.

Blood Glucose↗
PubMed1989

Transdermal therapeutic systems and rate controlled drug delivery.

One of the key design features of transdermal therapeutic systems, namely the system rate-control, and its impact on systemic therapy, are reviewed. Specifically, TTS(scopolamine) and TTS(estradiol) are evaluated as examples of the rate-controlled transdermal products. The use of these TTS products has resulted in controlled plasma concentration of drug and reduced side effects by the use of TTS(scopolamine) and more physiologic estradiol to estrone ratio with the transdermal dosage form of estradiol.

Administration, Cutaneous↗
PubMed1981

The osmotic pump: novel research tool for optimizing drug regimens.

Evaluation and selection of drugs, and determination of the optimal regimen, for controlled-release pharmaceutical products necessitate the reassessment of the pharmacology of drugs delivered at controlled rates. We have developed osmotic pumps for this purpose. These pumps, 1- and 2-week duration implants for animal studies, and 12- and 24-hour forms for oral and rectal administration in clinical studies, provide precise, accurate control over rate and duration of systemic or local drug delivery.

Animals↗