Biomedical subjects

S Itoi

Publications and source records attributed to S Itoi.

12 recordsLinked to original sources

PubMed1991

Bestatin administration and the change in cellular immunity.

The change in cellular immunity by Bestatin (ubenimex) treatment--30 mg/day orally--was investigated in 23 gastrointestinal cancer patients for: 1), functional T cell subsets; 2), IL-2 receptor; 3), PHA-induced blastogenesis; and 4), PPD skin reaction. The absolute number of helper T cells (Th) and cytotoxic T cells (Tc) increased in 74 and 79% of cases, respectively, compared with pretreatment values. On the other hand, the absolute number of suppressor T cells (Ts) decreased in 79% of cases. IL-2 receptor increased in 56% of patients, PHA blastogenesis increased in 67% of patients and PPD skin reaction was elevated in 75% of cases comparing to pretreatment values. These results suggest that Bestatin could increase cellular immunity in cancer patients.

Antibiotics, Antineoplastic↗

PubMed1986

[Cryoprostatectomy--practice and problems].

We reviewed 479 cases of cryoprostatectomy, 361 of which were performed using the 1-or 2-stage refreezing method, and 118 cases which were done by freezing only once. The refreezing methods gave better clinical and radiographic results as compared with the once-freezing method. As complications were seen in 20% of the cases in which the refreezing method was used and 10% of those in which the once-freezing method was used. Sonographic control was useful for the prevention of complications.

Aged↗

PubMed1979