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Biomedical subjects

S Iurato

Publications and source records attributed to S Iurato.

At least 37 records · Page 2Linked to original sources
PubMed1982

Tympanic membrane homografts. Histological findings in a human case.

The structure of a human tympanic membrane has been studied with the electron microscope 12 months after implantation. The lamina propria of the epidermis and the connective submucosal layer were thicker in the homograft than in the normal tympanic membrane. Creeping substitution in the fibers of the outer radial and inner circular layers was not observed but cannot be excluded. The protective role of the skin of the external meatus and of the epithelial cells of the mucosal layer has been noted.

Connective Tissue↗
PubMed1981

An ultrastructural study of the calcification process in tympanosclerotic tissues.

The alterations of the connective tissue components in the middle ear during tympanosclerosis have been analyzed at ultrastructural level. The final steps of this pathological condition are characterized by the disappearance of the blood vessels, cellular degeneration, hyalin degeneration, and calcification. The different features of the inorganic deposits and the cellular origin of the organic structures involved in the calcification process are described.

Basement Membrane↗
PubMed1978

Distribution of the crossed olivocochlear bundle in the chinchilla's cochlea.

The efferent crossed olivocochlear bundle (COCB) was transected in the brain stem of the chinchilla, and the animals sacrificed 7 to 96 days later. Electron microscopy revealed that all the large efferent nerve endings on outer hair cells in the basalmost 2 mm (round window region) of the cochlea had degenerated, 87.5% in the remainder of the first turn, 70% in the second turn and 43% in the third turn. Only a few degenerating nerve fibers were seen in the medial spiral tract (inner spiral and tunnel bundles) of the experimental animals. Nerve fibers were counted in the medial spiral tracts of the cochleas of control animals as well as in those animals whose COCB had been transected. There were considerable individual variations in the fiber numbers, and statistical analysis showed no significant difference between the numbers of nerve fibers in normal and experimental animals. The cochlear microphonics (CM) and nerve action potentials (AP) of acute animals were assessed before and after COCB section. The CM and AP of the chronic experimental animals were compared with responses from normals. Overall, no changes in a physiological response of the anesthetized chinchilla could be attributed to complete section of the COCB.

Acetylcholinesterase↗
PubMed1976

Lysosomes in normal and degenerating neuroblasts of the chick embryo spinal ganglia. A cytochemical and quantitative study by electron microscopy.

Lysosomes were studied by both cytochemical and quantitative methods in normal and degenerating neuroblasts of the chick embryo spinal ganglia. In normal neuroblasts (primitive and intermediate neuroblasts) both primary lysosomes and autophagic vacuoles were found; these organelles were usually located in the region containing the Golgi complex. In degenerating neuroblasts lysosomes appeared sharply decreased in number with respect to normal neuroblasts. Moreover, lysosomes were always evident as intact organelles surrounded by a membrane and the acid phosphatase activity appeared localized exclusively within these bodies. A diffuse distribution of acid phosphatase activity was only found in a limited number of cases during the terminal stage of the process. Possibly in these cases the enzymatic activity depended on the cells which enveloped the degenerated neuroblast remnants. The present results indicate that lysosomes do not play a primary role in the degenerative process studied.

Acid Phosphatase↗