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Biomedical subjects

S Ivanov

Publications and source records attributed to S Ivanov.

At least 19 recordsLinked to original sources
PubMed1992

Influence of demetallization of hydrogenated sunflower oil on changes in the forms of heavy metals and their pro-oxidative effects.

The effect of removing heavy metals from hydrogenated sunflower oil using a method based on changes in the contents of the various forms of the heavy metals copper, iron, zinc and nickel and their respective pro-oxidative effects was studied. A high degree of removal of dissociated and bounded ions was observed for hydrogenated oil, while there was no change in the contents of the co-ordination form. The pro-oxidative effect of the dissociated ions and of the bound metal ions in hydrogenated oil decreased nine-fold and seven-fold, respectively, compared with that of the non-hydrogenated oil, as a result of which the oxidation stability of hydrogenated oil increased two-fold. Comparative studies confirmed as appropriate the use of wash waters and auxiliary solutions that do not contain heavy metals for the processing of the hydrogenate after the classical technology.

Copper↗
PubMed1992

[The surgical treatment and results in patients with leukoplakia vulvae].

For period from 1976 to 1988 in the Clinic of Gynecology were treated 78 patients (women--31-74 years old) with leukoplakia vulvae. 61 patients (77.2%) were subjected to classical simple vulvectomy. 18 patients (22.8%) were subjected to simple vulvectomy according to Abitbol. Per primam was closed operative sore at 12 patients, operated by classical vulvectomy and at 8 patients, operated according to Abitbol. Per secundam was closed operative sore at 49 women from first group and at 10 from second group. Stenosis vulvae was shown at 4 women (5%) and at 7 (8.9%) was developed recurrence, who was applied to accomplish a repeated treatment. Good results were educated from vulvectomy according to Abitbol. This vulvectomy was recommended from authors.

Adult↗
PubMed1992

[Cardiotocographic control during labor].

The authors discuss different aspects of intrapartum foetal monitoring. The scientific basis of foetal intrapartum foetal monitoring are pointed out. The authors present three groups of cardiotocographic signs which should alarm the obstetricians: warning signs, threatening signs and clear signs for foetal distress. The authors discuss also the specific characteristics of the cardiotocographic record of premature fetus during pregnancy and labour. It is pointed out that the intrapartum foetal monitoring and the correct interpretation of the cardiotocographic record lead to better perinatal results.

Cardiotocography↗
PubMed1992

[The posttherapy survival of patients with invasive cancer of the vulva].

The treatment results and five-years survival are studied in 157 patients with invasive vulvar cancer treated for the period of 1979-1988 in Gynaecological Clinic of the National Oncological Center Institute in Sofia. The general five years survival is 59.2%. The highest is the survival of the patients with first clinical stage--79.55%. The best treatment results are by patients treated with radical vulvectomy and regional lymph node dissection, without histological founded metastases in the extirpated lymph nodes--69.24% five years survival. The authors show some better results because of the better early diagnosis of the disease and the improved therapeutical methods.

Bulgaria↗
PubMed1992

gamma-Glutamyltranspeptidase and dipeptidyl peptidase IV activity in the serum of normal and hepatoma-bearing chickens and in the plasma membranes from liver and hepatoma Mc-29.

Investigations on the activity of gamma-glutamyltranspeptidase (GGT) and dipeptidyl peptidase IV (DPP IV) in the serum of healthy chickens and those bearing hepatoma Mc-29, and in liver and hepatoma plasma membranes were carried out. There was no difference in the serum enzyme activities of control and tumor-bearing chickens but the activity of GGT was twice higher and that of DPP IV 20 times lower in hepatoma plasma membranes than in chicken liver plasma membranes. Using thin-layer analytical isoelectric focusing in agarose gels it was established that the pI range of GGT from host serum and hepatoma plasma membranes was shifted to more acidic values. This could be interpreted as a specific feature for this enzyme considered as a tumor marker.

Animals↗
PubMed1991

[The antenatal diagnosis of the sex of the fetus by the cytological determination of sex chromatin].

Forty women between 17 and 23 weeks' gestation were included in the study, whose interruption of pregnancy was performed by medical and social indications. The method of Aburel-Atanasov was used as in 10 ml of the removed amniotic fluid sex chromatin was examined cytologically on cellular smears. Staining and determination of sex chromatin was made by the method of Dokumov. The fetus of male sex, when there was no sex chromatin, but the sex was female, when it was present in various percentage of cells. The genuine sex of the fetus was determined after interruption of pregnancy. Coincidence of cytological and genuine sex of the fetus was found in 36 cases (92.31%), but the sex was determined not exactly in 3 cases (7.69%). There was no sufficient material for preparation of high-grade cytological smears in one case. 14 out of 40 fetuses were of female sex (with sex chromatin in 28.57% of cells on the average) and 25 of male sex. The significance and advantages of the method in comparison with other methods for determination of fetal sex at the same term of pregnancy are discussed.

Amniotic Fluid↗
PubMed1991

[A modified Sugiura operation].

This is the first report in Bulgaria of the application of the modified method of Sugiura. The operation is less traumatic than the original one, the postoperative mortality is essentially reduced, patient survival to 7 years is increased and there is no encephalopathy. This operation is technically easier to perform than splenorectal anastomoses and may be performed both as planned and emergency intervention. Two personal observations on two patients operated by the modified technique of Sugiura are reported. The results were very good.

Adult↗
PubMed1991

[Our initial experience with Shouldice's hernioplasty].

For the first time in Bulgaria the authors herniotomy of inguinal hernias by the method of Shouldice. This method is anatomo-physiological and is pathogenetically well-grounded. Shouldice's method is considered the method of choice in inguinal hernias.

Adult↗
PubMed1991

[A modified Sugiura operation].

The modified method of Sugiura is reported for the first time in Bulgaria. The operation is less traumatic than the original one, the postoperative case fatality rate is lower, patient survival rate up to 7 years is high and there is no encephalopathy. This operative technique is more practicable than splenorenal anastomosis and may be applied both for planned and for emergency operations. Two patients have been operated by the authors, using the modified technique of Sugiura, with very good results.

Adult↗
PubMed1991

[Antenatal diagnosis in cases of renal agenesis].

Renal agenesia was established by antenatal ultrasound diagnosis in 3 cases. The ultrasound image is characterized by the impossibility to visualize one or both fetal kidneys, oligohydramnios, lung hypoplasia and hypotrophy of the fetus. The possibilities for the earliest diagnosis as well as for interruption of pregnancy on account of the lethal outcome of the disease in the newborn are discussed.

Adult↗
PubMed1991

[Malignant non-Hodgkin's lymphomas in abdominal surgery: apropos 3 cases of Burkitt's lymphoma].

On the occasion of three observations of the extremely rare and malignant Burkitt's lymphoma, the authors record their 7-year experience in the operative treatment of 22 patients with non-Hodgkin's malignant lymphomas. Proceeding also from data available in the current literature, the most frequently encountered syndrome-complex is presented, the knowledge of which is of major importance for the early diagnosis, resp. for the results of combined treatment. The possibilities of the operative treatment are evaluated. In the authors' series it was radical in 31.8 per cent of the cases with 13.6 per cent early postoperative lethal outcome and 5.2 months average postoperative survival rate. Proceeding for the rarity of the disease in everyday surgical practice and that it is poorly known, but has become a nosologic entity of increasing interest, the authors have devoted the first part of their article to a discussion on the basic characteristics of non-Hodgkin's malignant lymphomas and the modern achievements of their treatment.

Abdominal Neoplasms↗
PubMed1990

[Visceral pain].

Explore the source record for details and available documents.

Abdominal Pain↗
PubMed1990

[Transduodenal papillosphincteroplasty in the treatment of benign diseases of the terminal choledochus and papilla Vateri].

The modern state of the problem and the indications and contraindications for performing transduodenal papillosphincteroplasty are discussed. Personal experience is recorded with 67 transduodenal papillosphincteroplasties, performed for the period 1983-1989, against the background of 1091 operations on the hepatobiliary system, 171 of them on the extrahepatic bile ducts, performed during the same period. Proceeding from their own experience and from available data in the literature, the authors analyse and evaluate the surgical and nonsurgical methods of treatment of benign diseases of the terminal common bile duct and the duodenal papilla, manifested by stenotic lesions. The most important indications and contraindications for applying the different therapeutic methods are adduced. Remarks are made on the technique, which is of major practical importance and the respective conclusion is substantiated.

Adult↗
PubMed1990

[The remnant cystic duct in the syndromal complex of the postcholecystectomy syndrome].

Some modern aspects of the postcholecystectomy syndrome and the importance of d. cysticus remnant for its arising are discussed. Analysis is made of 13 patients with postcholecystectomy syndrome surgically treated at the Department of Propedeutics of Surgical Diseases, Research Institute of Surgery, over the period 1983-1989. Results are reported of a study of 180 operated patients (cholecystectomized), in in 7.8 of whom low-grade postcholecystectomy syndrome developed. Accent is laid on the importance of the intraoperative diagnosis and on some characteristics of technical nature, requiring precision in processing d. cysticus. Conclusion is drawn, aimed at reducing to a minimum the percentage of postcholecystectomy syndrome.

Adult↗
PubMed1990

[Obstetrical problems in family planning].

The author describes medico-social aspects of the family planning, reproductive health of the woman and some problems of the perinatal period of the newborn. Rational planning of the family leads to favourable conditions and possibilities for protection of the health of the pregnant woman, mother and children, for diminution of abortions, for extending natural feeding of the suckling baby. Effects of some factors in active and right family planning and their impact on the health of the woman and on the level of the basic obstetric parameters: maternal mortality, perinatal mortality, sterility, etc. are analysed.

Bulgaria↗