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Biomedical subjects

S J Bennett

Publications and source records attributed to S J Bennett.

13 recordsLinked to original sources
PubMed1992

The effects of lignocaine on human sperm motility.

OBJECTIVE: The purpose of this study was to assess the motility of human sperm incubated with various concentrations of lignocaine. METHODS: Eleven semen samples with a sperm density greater than or equal to 20 x 10(6) ml and progressive motility greater than or equal to 40% were prepared using a swim-up technique. Aliquots from each sample were incubated for 4 hr under capacitating conditions with lignocaine concentrations of 100, 10, 1, and 0.1 microgram/ml and without additional lignocaine as a control. Digital computerized motion analysis was performed on all samples at 1, 2, and 4 hr after the addition of lignocaine. RESULTS: After 2 hr of incubation a significant (P less than 0.05) increase in the percentage of sperm with a curvilinear velocity greater than 100 microns/sec was observed in those samples incubated with 100 micrograms/ml lignocaine. This stimulatory effect was no longer apparent after a further 2 hr of incubation. No other significant changes were identified in any of the motility parameters examined. CONCLUSIONS: No adverse effects on human sperm motility were identified during incubation with low concentrations of lignocaine. A transient stimulatory effect was observed at a lignocaine concentration of 100 micrograms/ml.

Humans↗
PubMed1992

Postmenopausal women. Factors in osteoporosis preventive behaviors.

Osteoporosis is a serious health hazard mainly affecting postmenopausal and elderly women. Osteoporotic fractures are one of the leading causes of morbidity and death in the elderly population. Prevention of further loss of bone mass in postmenopausal women can be achieved if women take estrogen replacement therapy, consume adequate levels of calcium, exercise regularly, and practice healthy lifestyle behaviors. Elderly women need to follow the same strategies as postmenopausal women with more emphasis on prevention of falls.

Aged↗
PubMed1977

Elution of tumor-directed antibody from kidneys of mammary tumor-bearing mice.

Immunoglobulin-containing eluates, prepared from kidneys of Paris RIII mammary tumor-bearing mice approximately 10 months old, were incubated with frozen sections of mouse mammary tumor and normal lactating mammary gland and examined by immunofluorescence. The eluates diffusely strained the tumor but did not stain the nonneoplastic lactating mammary gland. Mammary tumor and normal lactating mammary gland were both stained by an antiserum to mammary tumor virus (MuMTV). The euglobulin portion of the eluates, when fractionated on a Sephadex G-200 column, yielded an IgG fraction which was shown by immunodiffusion to react with Paris RIII mammary tumor extract and with anti-mouse globulin but not with nonneoplastic mouse tissue extracts. Since the lactating mammary glands of these animals contain MuMTV, the antibody-containing fraction eluted from the kidneys appeared to be tumor directed rather than virus directed.

Animals↗
PubMed1977

Carcinoembryonic antigen: immunohistologic identification in invasive and intraepithelial carcinomas of the lung.

A total of 58 pulmonary lesions from 48 patients were examined for carcinoembryonic antigen (CEA). The three-layer immunoperoxidase procedure for antigen detection was used with a monospecific anti-CEA antiserum. The control serum was the same antiserum with its specificity removed by affinity chromatography. Normal goat serum was also used as a control. Carcinoembryonic antigen was present in the majority of pulmonary adenocarcinomas and generally absent in the squamous cancers. The major exception was in the well-differentiated squamous lesions where CEA was occasionally found in the keratinizing areas. Of special interest was the finding of CEA in all areas of intraepithelial squamous neoplasia studied.

Adenocarcinoma↗
PubMed1976

Electron microscopy and immunofluorescence of glomerular immune complex deposits in cancer patients.

Kidneys of 29 patients without clinical renal disease were studied by electron microscopy for the presence of glomerular basement membrane deposits: those from 11 of 20 patients with cancers of various sites, but only 1 of 9 patients without cancer contained electron-dense subendothelial deposits. The majority of these kidneys gave positive immunofluorescent reactions for immunoglobulin and complement. However, among a number of the cases studied, a lack of correlation between electron microscopic and immunofluorescence findings has yet to be investigated. Although the number of patients in this study is small because of the difficulty in obtaining tissue for electron microscopy, it is postulated that the deposition of immune complexes in the kidney occurs with a high frequency among cancer patients. The kidneys may thus be a valuable source for isolating tumor-associated antigens and corresponding antibodies.

Adolescent↗
PubMed1975

Adenocarcinoma of the small intestine arising in Crohn's disease. Demonstration of a tumor-associated antigen in invasive and intraepithelial components.

A segment of small intestine surgically removed from a man with intestinal obstruction was found to have coexisting regional enteritis and an invasive adenocarcinoma associated with an area of intraepithelial neoplasia. The cells of the adenocarcinoma and the intraepithelial neoplasia contained a tumor-associated surface antigen capable of reacting with an antiserum prepared against a colonic carcinoma. The importance of thorough sampling of specimens of regional enteritis in accurate reporting of the incidence of carcinoma is stressed, as is the use of immunohistologic techniques as an adjunct to the morphologic diagnosis of preinvasive neoplasia.

Adenocarcinoma↗
PubMedDate not supplied

Seeking-out behavior: criterion for success in clinical learning experiences.

Seeking-out behavior, defined as a collective group of behaviors practiced by the nursing student when planning and implementing care for clients, is proposed as the successful criterion for clinical learning experiences. The author describes relevant attributes and implications of seeking-out behavior. A model of clinical teaching is proposed in which seeking-out behavior is a key concept. The model is evaluated using Fawcett's criteria of pragmatic adequacy.

Clinical Competence↗
PubMedDate not supplied

Perceived threats of individuals recovering from myocardial infarction.

Lazarus' phenomenological theory of stress and coping provided the basis for this descriptive study of perceived threats after myocardial infarction (MI). Sixty-four post-MI subjects enrolled in phase II cardiac rehabilitation programs identified threats they had experienced in the past month. Perceived threats were defined as situations that were difficult or troubling to the individual and were described by respondents in narrative form. Degree of threat was then measured by one item on which subjects indicated the degree of concern the threatening event had caused them. Responses to the one item were analyzed and categorized into the following five areas: physical problems; medical therapy/self-care; work/physical activity; interpersonal/family; and financial. The results provide an overview of the multiple concerns individuals deal with after a major life-threatening cardiac event.

Adaptation, Psychological↗
PubMedDate not supplied

Pericarditis. Nursing care makes the difference.

Nursing care of the patient with pericarditis, a commonly seen syndrome in the clinical setting, is discussed in this article. Pericarditis is particularly prevalent in the patient following myocardial infarction. Astute nursing assessment is described. Goals of nursing care include management of pain, maintenance of adequate cardiac output, and provision of support to manage anxiety and fear. Interventions to meet the goals, as well as outcome criteria, are identified.

Humans↗
PubMedDate not supplied

Blending the entrepreneurial and faculty roles.

A changing health care system makes this an opportune time for nursing faculty to use their expertise to improve the public's health care. The author explores the benefits to the individual, the profession, the university, and the health care system of merging the entrepreneurial philosophy and role with the traditional nurse faculty role.

Economics, Nursing↗