PubMed HealthSearch

Biomedical subjects

S J Benson

Publications and source records attributed to S J Benson.

6 recordsLinked to original sources

Satellite system addresses rural health problems.

The University of Nebraska Medical Center uses the recently established NEB*SAT state-owned satellite television system to transmit several types of educational presentations to rural Nebraska. The system represents the latest in a series of pioneering two-way television activities which have opened educational opportunities to students and professionals off-campus. Compressed video, transmitted via the NEB*SAT system, allows us to share credit courses in nursing and medical technology, administrative meetings, case conferences, and continuing education programs.

Education, Medical

Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells.

The effects of nonesterified fatty acids (NEFA) in modulating testosterone synthesis stimulated by luteinizing hormone (LH, 10 ng/sample) were investigated in isolated adult mouse Leydig cells. LH-stimulated testosterone production was inhibited by triglycerides (0-500 mg/dl, 50 mg/dl, 94% of the control and 500 mg/dl, 40%) and by a mixture of NEFA (100 microM, 70% of control, 200 microM, 54%, and greater than 200 microM, less than 50%). Oleic acid was a more potent inhibitor than linoleic, stearic, or palmitic acids. 8-Bromoadenosine 3',5'-cyclic monophosphate (8-BrcAMP, 5 mM) stimulated testosterone production comparable to LH but failed to reverse the inhibition of steroidogenesis produced by the NEFA. The inhibition produced by NEFA was dependent on extracellular Ca2+; and a Ca2+ channel antagonist, verapamil (10 microM), enhanced the inhibition of chylomicrons and fatty acids. 22(R)-hydroxycholesterol (10 microM) reversed the inhibition produced by NEFA. The inhibitory effects of NEFA were reversible by removal of the fatty acids. The results indicate that NEFA are potent modulators of testosterone synthesis in Leydig cells stimulated with either LH, cAMP, or intracellular Ca2+. NEFA inhibit steroidogenesis at one of the steps preceding conversion of cholesterol to pregnenolone.

8-Bromo Cyclic Adenosine Monophosphate

"Good" TV visuals: do they make a difference?

Media producers generally urge health science instructors to plan television visuals that conform to accepted ideas of what is "good" for television. Experiments in a class of nursing students taught entirely by television tested whether learning was affected by differences in visual aspect ratio, color, and seeing the instructor on the screen. It was found that alterations in these characteristics did not affect performances on post-tests, but the students did have definite preferences in some areas.

Chemistry

Using media in rural clerkships.

To enhance the educational value of rural clerkships for health professions students, the Biomedical Communications Division of the University of Nebraska Medical Center explored ways of providing instructional media to off-campus training sites. Faculty and community hospitals in rural areas were surveyed to identify appropriate topics. Videocassettes and slide-tape packages were previewed, evaluated, and purchased when acceptable. The packages were stored at Biomedical Communications. Off-campus faculty and students were encouraged to order media for use during preceptorships, but few took advantage of the opportunity. The greatest use of media occurred when packages were made available on-campus and students were encouraged to view them before or after rural clerkships.

Attitude

Diagnostic value of a chemistry test profile.

Serum chemistry test results were correlated with discharge diagnoses of 4,295 persons admitted to an acute care general hospital in a seven-month period. The diagnostic value of the test results, separately and in combinations of up to 12 tests, were calculated at each of ten levels as measured from the mean of normal in standard deviations. All patients had a serum profile consisting of total calcium, inorganic phosphorus, glucose, urea nitrogen, uric acid, cholesterol, total protein, albumin, total bilirubin, alkaline phosphatase, lactic dehydrogenase, and glutamic oxaloacetic transaminase levels. Analysis by manual and computer technics is illustrated. Computerized analysis of a chemistry profile is reported as a list of diagnostic possibilities in ranking order, with the calculated probability for each. In this preliminary report individual diseases are replaced by categories of disease taken from The International Classification of Diseases, Adapted (ICDA).

Adolescent