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Biomedical subjects

S J Butterworth

Publications and source records attributed to S J Butterworth.

11 recordsLinked to original sources
PubMed2004

Slipped capital femoral epiphysis in dogs.

In a retrospective review of 43 femoral fractures, three dogs had separation of the femoral capital epiphysis from the metaphysis in the absence of trauma. Two of these dogs also had evidence of pathology in the contralateral femoral neck including, in one dog, displacement of the capital epiphysis in relation to the metaphysis without actual separation. The case histories, radiographic features and histopathological findings of these cases were reviewed and compared with previous cases of slipped capital femoral epiphysis (SCFE) reported in dogs and also with SCFE in children. Pre-slip, acute, chronic and acute-on-chronic slips were Identified. Based on the cases reviewed, the authors advise internal fixation of stable slipped epiphyses in dogs. This may also be appropriate for unstable separations, although resorption of the femoral neck may preclude stable fixation and necessitate femoral head and neck excision.

Animals↗
PubMed2001

Incomplete humeral condylar fractures in the dog.

The details of eight dogs (11 elbows) referred to the authors with lameness relating to elbow pain associated with incomplete fracture of the humeral condyle were reviewed. In all cases, a diagnosis was reached by radiographic examination, with the pathognomonic feature being a radiolucent line, in the sagittal plane, through the condyle. Treatment involved placement of a transcondylar bone screw with or without bone tunnels being created parallel to this implant. Six dogs (nine elbows) made a complete recovery without subsequent complications.

Animals↗
PubMed2000

Radial carpal bone fractures in 15 dogs.

Between 1977 and 1992, 15 adult dogs were presented to the Universities of Bristol, Glasgow, Liverpool and London with fractures of the radial carpal bone which had occurred without a known episode of violent trauma. Eleven of the dogs were boxers and the other breeds affected were a Pharaoh hound, rottweiler, springer spaniel and a greyhound. The condition was bilateral in three cases. Eleven dogs were treated surgically by cast immobilisation (four cases), fragment removal (one case), lag screw fixation (three cases), pan-carpal arthrodesis (one case) and lag screw reduction followed by pan-carpal arthrodesis (two cases). The remaining four dogs were treated conservatively with rest and tactical use of non-steroidal anti-inflammatory drugs. Follow-up periods ranged from two months to 11 years. Varying degrees of lameness, which tended to be exacerbated by exercise, persisted in all cases. The radial carpal bone appears to have at least three separate centres of ossification which eventually fuse; their planes of fusion correspond approximately to the two main fracture lines. These areas of fusion could be weak points within the radial carpal bone.

Animals↗
PubMed1999

Management of cervical spondylopathy-associated intervertebral, disc protrusions using metal washers in 78 dogs.

Intervertebral 7.5 mm (n = 75) and 6.0 mm (n = 22) metal washers were used to distract intervertebral spaces in 78 consecutive cases of canine cervical spondylopathy-associated disc protrusions, where myelography had demonstrated traction-responsive spinal cord compression. Nineteen dogs had compressive lesions at two sites. Fifty lesions were evaluated myelographically on immediate postoperative radiographs; of these, 32 compressions had been eliminated and 18 had been reduced. Euthanasia was performed in nine dogs within six months of surgery and 15 dogs had varying degrees of neck pain during this period. Long-term follow-up information was available on 65 dogs nine to 70 months following surgery (median 32 months). Sixty-three of these dogs improved postoperatively. Neurological function subsequently deteriorated in 17 dogs 10 to 59 months following surgery (median 34 months). Eight of these 17 cases had further myelographic investigations and all had additional disc protrusions with no evidence of cord compression at the previous sites of surgery. The remaining nine cases had a deterioration in hindlimb function but were not investigated further.

Animals↗
PubMed1998

Characterization of wear debris associated with aseptic loosening of a canine hip prosthesis.

A 12-month-old Golden Retriever bitch underwent unilateral hip arthroplasty following a diagnosis of coxofemoral osteoarthritis secondary to hip dysplasia. The hip prosthesis underwent aseptic loosening and was removed 6 months after implantation. Synovial biopsies taken at that time revealed scattered foci of granulomatous inflammation associated with intra-cytoplasmic and extracellular particulate material. Electron microscopical analyses demonstrated that this material contained cobalt, chromium, titanium and zirconium, which was probably wear debris from the loosened prosthesis. In human patients with hip arthroplasty, widespread dissemination of wear debris from loosened prostheses occasionally occurs, with an increased prevalence of neoplasia. A similar phenomenon may be predicted to occur with the increasing use of hip arthroplasty in the dog.

Animals↗
PubMed1995

Multiple discospondylitis associated with Aspergillus species infection in a dog.

Multiple discospondylitis was diagnosed in a four-year-old, neutered female German shepherd dog which had suffered intermittent pain of the axial skeleton for 10 months, which was followed by the sudden onset of paraplegia associated with the rupture of an affected disc. After surgical and medical management the dog began to improve but then deteriorated as a result of a pathological fracture of the fifth lumbar vertebra. A histological examination revealed fungal hyphae at the sites affected radiographically and they were identified by immunohistochemistry as Aspergillus species. No fungal hyphae were identified in other tissues. This is the first report of canine mycotic discospondylitis in the United Kingdom.

Animals↗
PubMed1994

Postoperative analgesic and sedative effects of carprofen and pethidine in dogs.

Forty dogs undergoing a variety of orthopaedic surgical procedures were randomly assigned to one of two analgesic protocols, receiving either pethidine at 2 mg/kg pre-operatively and 3 mg/kg postoperatively, or carprofen, a new non-steroidal anti-inflammatory drug at 4 mg/kg pre-operatively. Analgesia and sedation were assessed after the operations under double blind conditions using a discontinuous scoring system and a visual analogue scale. There was good agreement between the two scoring systems, and a statistical analysis of the visual analogue scores showed that carprofen provided slightly better pain relief than pethidine and produced less sedation. Carprofen provided good analgesia during the 18 hours the dogs were in hospital and no adverse side effects were observed.

Analgesia↗
PubMed1992

A review of the usefulness of myelography in 50 dogs.

Fifty dogs showing clinical signs of spinal disease were investigated by myelography, using iopamidol. In 27 cases the technique was considered worthwhile. Of the 19 dogs not subjected to surgery or euthanasia as a result of the findings, three suffered seizures during recovery from anaesthesia, eight deteriorated in neurological condition and one suffered permanent respiratory arrest as a result of extensive subarachnoid haemorrhage.

Animals↗