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Biomedical subjects

S J Fomon

Publications and source records attributed to S J Fomon.

At least 73 records · Page 4Linked to original sources
PubMed1980

Effect of feeding frequency on growth and body composition of gastrostomized rat pups.

Two groups of rat pups were gastrostomized at 24 hours of age and formula-fed each hour or once every 6 hours a daily intake equal to 33% of their body weight. They were killed at age 5 to 7 days when body weight had reached twice that at time of gastrostomy; organ weights, body composition and hepatic activity of glucose-6-phosphate-dehydrogenase (G-6-PD) and alpha-glycerophosphate dehydrogenase (alpha-GPD) were determined. The stomach, small intestine, liver and spleen of pups fed 4 times each day were significantly larger than those of pups fed hourly. Food efficiency (gain/kcal) of pups fed each hour was significantly greater than that of pups fed every 6 hours; however, because pups fed each hour gained more water and less fat, an estimate of the percentage of energy intake utilized for growth was significantly less for these animals than for those fed every 6 hours. Concentration of calcium was greater and concentration of sodium was less in the carcasses of pups fed each hour than in the carcasses of pups fed 4 times daily. Total liver activities of G-6-PD and alpha-GPD were significantly less in pups fed each hour but the activity of these enzymes expressed per milligram of liver protein did not differ significantly between the two feeding groups.

Animals↗
PubMed1980

Factors influencing food consumption in the human infant.

It is reported that feeding studies of normal infants, while sharing a correlation between fatness at 112 days and fatness at eight years, do not support the hypothesis that fatness in later life differs according to breast or bottle feeding of infants.

Aging↗
PubMed1979

Methionine fortification of a soy protein formula fed to infants.

Data from study of nine normal full-term infants fed a soy isolate-based formula unsupplemented with methionine were compared with similar data from study of 10 similar infants fed the same formula supplemented with L-methionine and with data from previous studies of larger groups of infants receiving various other feedings. Food intake, growth, and serum chemical values were studied from 8 through 111 days of age. In addition, nitrogen balance studies were carried out. Statistically significant differences were as follows: lesser weight gain per 100 kcal by infants fed the unsupplemented soy isolate-based formula than by infants fed milk-based or other soy isolate-based formulas; lesser serum concentrations of albumin at age 28 days by infants fed the unsupplemented soy isolate-based formula than by breast-fed infants; greater serum concentrations of urea nitrogen by infants receiving the unsupplemented soy isolate-based formula than by those receiving the same formula supplemented with L-methionine. A number of other differences was noted but were not statistically significant. The results suggest that normal infants fed a formula providing 2.25 /100 kcal of a soy protein isolate not fortified with methionine performed less well during the first 6 weeks of life than did breast-fed infants and infants fed milk-based formulas or other soy isolate-based formulas fortified with methionine. The limiting nutrient appears to have been methionine.

Aging↗
PubMed1977

Nitrogen balance studies with normal children.

A total of 1148 nitrogen balance studies were conducted in 100 boys and 23 girls 1 to 11 years old. Mixed, customary diets supplied between 8.9 and 21.4% of calories from protein. Duration of balance studies ranged from 72 hr in the youngest subjects to 120 hr in older children. Regressions and 95% confidence intervals of nitrogen retention on nitrogen intake are presented. The slope of the regression was significantly greater for children 12 to 18 months old than for children of other age groups. Correlation coefficients between various parameters of nitrogen balance and energy intake are presented. Although variability in results of nitrogen balances within subjects appears to be rather large, a significant difference between subjects was observed.

Absorption↗
PubMed1977

Skim milk in infant feeding.

Skim milk in infant feeding. Acta Paediatr Scand, 66:17, 1977. --Ninety-four infants were enrolled at 112 days of age in a study of food intake and growth and 88 were considered to have completed satisfactorily the planned 56 days of observation. The infants lived at home. Feedings consisted of a commercially available formula (Similac, 67 kcl/100 ml) or a slightly modified skim milk (Formula 305, 36 kcal/100 ml) and commercially prepared strained foods. Energy intake and gain in weight were significantly greater by infants fed Similac than by those fed Formula 305. Gain in length was nearly identical in the two feeding groups. During the 56 days of observation, triceps and subscapular skinfold thicknesses changed little in infants fed Similac but decreased approximately 25% in infants fed Formula 305. It is suggested that body fat stores of infants fed Formula 305 were mobilized to permit growth of fat-free tissue.

Adipose Tissue↗
PubMed1976

Influence of fat and carbohydrate content of diet on food intake and growth of male infants.

Two groups of normal fullterm infants were studied from 8 to 112 days of age while receiving formulas of the same caloric density and prepared from the same ingredients. A limited selection of strained foods were permitted. From the combination of formula and strained foods, one group received 29% of calories from fat and 62% from carbohydrate whereas the other received 57% from fat and 34% from carbohydrate. Fifteen infants in each group completed the study as planned. Energy intakes per kilogram and rates of gain in length and weight were similar in the two feeding groups.

Body Weight↗
PubMed1976

Body composition of the reference fetus.

Published data from chemical analyses of human fetuses have been utilized to construct a reference fetus of representative body composition. For gestational ages 24 through 40 weeks, body composition of the reference fetus is presented, including water, lipid, protein and major minerals. Concentrations of water, sodium, and chloride per unit of body weight decrease with increasing gestational age, whereas those of protein, lipid, calcium, phosphorus, magnesium and potassium increase. From the estimates of body composition at each age and from the gain in body weight, composition of gain and daily increments of body components have been calculated.

Adipose Tissue↗