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Biomedical subjects

S J Freeman

Publications and source records attributed to S J Freeman.

At least 73 records · Page 4Linked to original sources
PubMed1980

A controlled study of self-help intervention for widows.

The authors conducted a 2-year study of postbereavement adaptation in 162 widows. Sixty-eight were paired with a widow contact who provided emotional support and practical assistance. The differences between the women receiving intervention and the controls at 6, 12, and 24 months after bereavement suggested that those receiving intervention followed the same general course of adaptation as control subjects but that the rate of achieving landmark stages was accelerated for the intervention group. The Goldberg General Health Questionnaire and two indices derived from the study questionnaire confirmed the hypothesized "pathway" of adaptation" through intra- and interpersonal adaptation to resolution of overall distress and the effectiveness of the intervention.

Adaptation, Psychological↗
PubMed1980

An agency model for developing and coordinating psychiatric aftercare.

The development of coordinated systems for delivery of aftercare services to psychiatric patients has lagged far behind the theoretical emphasis on community maintenance. From a collaboration of 29 treatment and rehabilitation facilities, an independent agency was established to improve aftercare services in Metropolitan Toronto. Known as Community Resources Consultants, the agency was designed to facilitate and rationalize the use of existing services, to identify gaps in service, to initiate or cooperate in the development of new services, and to involve hospital and community service personnel in raising the level of expertise in the provision of aftercare. Formal and informal assessments indicate that CRC has had a positive effect on the provision of aftercare services and on professionals' level of awareness of aftercare priorities.

Adult↗
PubMed1980

A self-help program for widows as an independent community service.

Community Contacts for the Widowed, a self-help group in Toronto, offers individual and group counseling and volunteer work to widows. Beginning as a demonstration project funded by the provincial health ministry, the program became an independent charitable organization in 1976. Like many new self-help groups, the program employs peers who receive training in helping their clients by establishing a one-to-one supportive relationship. These peers, called widow contacts, also arrange group sessions and conduct community education on behalf of the program. Although reliance on a self-referral process limits the number of lower-class, immigrant, and other widows unwilling to reach out for help, since 1976 the program has helped more than 1500 women through their bereavement.

Adaptation, Psychological↗
PubMed1977

The final illness in cancer: the widow's perspective.

Widows of cancer patients were compared with other widows in general and with widows of men with chronic cardiovascular disease in particular, special attention being given to the vicissitudes of the final illness. Despite the recent emphasis on the need for open communication about the impending death between the dying patient and his family, interviews with 73 women whose husbands had died of cancer revealed that 40% of those who had been told their husband was dying refused to accept the warning. Only 29% of the couples openly discussed the possibility of the husband dying of his disease. More than half of those who did not talk with their husband about the impending death reported that this made no difference to their initial adjustment to bereavement. The stress for a woman of her husband's final illness leads to an especially difficult bereavement period; for example, significantly more widows of cancer patients than of patients with other illnesses perceived themselves to be in poor health during the initial bereavement period. Some of the problems specific to cancer patients and their families are described, along with recommendations for their alleviation.

Adult↗
PubMedDate not supplied

Post-implantation whole embryo culture and the study of teratogenesis.

The two major applications of whole post-implantation rat embryo culture (WEC) are as a test for teratogenicity in safety evaluation studies and as a tool in the investigation of mechanisms of teratogenesis. As a test system, WEC possesses many of the characteristics necessary for an in vitro screen. However, its use on a large scale is disqualified for reasons of cost and the demand for technical expertise to perform cultures and interpret findings, compared with other in vitro teratogenicity screens, although its use might be preferred when only a few compounds require testing. The major value of WEC lies in its use for studying mechanisms of teratogenesis. The opportunity to study the embryo in isolation and the versatility afforded by the technique offer considerable advantages in this context.

Abnormalities, Drug-Induced↗
PubMedDate not supplied

Inhibition of yolk sac function in late gastrulation rat conceptuses as a cause of teratogenesis: an in vivo/in vitro study.

A rabbit anti-rat yolk sac antiserum, administered by intraperitoneal injection at 0.25 mL/100 g bodyweight into 8.5-day pregnant rats, resulted in a resorption incidence of 20%, and growth retardation and malformation of all surviving fetuses at term. In all subsequent experiments, pregnant rats either received this same dose of antiserum at 8.5 days or were untreated. When 9.5-day rat conceptuses were cultured for 48 h in a medium containing serum from a 9.5-day pregnant rat that had been treated with antiserum, development was severely abnormal, regardless of whether conceptuses were explanted from antiserum-treated or untreated dams. In contrast, culture for 48 h in serum from untreated 9.5-day pregnant rats resulted in normal growth and development of conceptuses explanted from untreated dams, and in slight growth retardation and dysmorphogenesis in 9.5-day conceptuses explanted from antiserum-treated dams. In the former, development was similar to that attained by 11.5-day conceptuses from untreated dams; in the latter, development was appreciably better than in 11.5-day conceptuses from antiserum-treated dams. These results indicate that the critical period of exposure of embryos in utero to teratogenic antiserum after administration to the 8.5-day pregnant rat is longer than 24 h and that a significant insult is delivered to the conceptus before 9.5 days ea. Using 9.4-day ea conceptuses in culture, pinocytosis (uptake of 125I-labelled polyvinylpyrrolidone) by the yolk sac, and its inhibition by antiserum, was demonstrated. No pinocytic activity was evident in the embryo itself. These data support the hypothesis that anti-yolk sac antiserum exerts its teratogenic action by inhibiting the nutritional function of the yolk sac during early organogenesis.

Animals↗
PubMedDate not supplied

The use of groups in the rehabilitation of amputees.

There is a complex interplay between physical and emotional factors in the rahabilitative process after amputation of a limb. Although this is recognized by those working in the field of rehabilitation medicine, an overview of the literature indicates that there is comparatively little psychosocial research, education, and innovative programming. The authors have initiated such a program and have incorporated it into the routine of an inpatient amputee unit. The approach involves the utilization of basic techniques of supportive group therapy in the discussion of recurrent themes which have emerged as major concerns among amputees. Experiences amputees help new patients to anticipate potentially stressful situations, thus encouraging increased reliance. Having professionals present allows for the clarifying of medical and/or technical issues and the group setting provides a relaxes atmosphere conducive to educative discussion of physical and psychosocial concerns.

Adaptation, Psychological↗
PubMedDate not supplied

The effectiveness of psychosocial support during post-surgical treatment of breast cancer.

Sixty-four women undergoing radiotherapy for breast cancer in a residential setting which offered structured cognitive and emotional support, are compared for level of psychological distress and satisfaction with staff support with 104 women living at home during treatment. The outcome measures were the 30-item Goldberg General Health Questionnaire (GHQ) and a 5-item author-constructed Treatment Support Index. A surprisingly large percentage of the sample did not, at any time, manifest appreciable psychological distress. For those women whose level of distress changed by a GHQ score of 3 or more over the three week course of treatment, residence in the Lodge was associated with decreased risk of change for the worse, and increased probability of change for the better. Results from the Treatment Support Index indicate that a significantly greater percentage of Lodge residents than non-residents were satisfied with the quantity, quality, and/or diversity of support available to them.

Adaptation, Psychological↗