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Biomedical subjects

S J Galloway

Publications and source records attributed to S J Galloway.

9 recordsLinked to original sources

Minimal asymmetry of the brain: a normal variant.

Normal cerebral asymmetry, well-known to neuroradiologists, is not widely recognized by radiologists in general. In our review of CT brain scans, 31 of 300 patients with a negative neurologic examination and no history of birth injury, head trauma, or seizure had recognizable asymmetry of the frontal horns of the lateral ventricles. The right frontal horn and the right cerebral hemispheres were larger than the left twice as often as left were larger than right. The right frontal lobe was wider than the left in 44% of patients and extended as far anteriorly or more anteriorly than the left in 22% of patients. The right central hemispheric mass tended to be wider than the left, resulting in slight displacement of the pineal gland to the left, in approximately 45% of cases. The posterior end of the left Sylvian fissure projected farther posteriorly in 10% of the patients. Occipital petalia and a more posterior position of the calcified glomus of the choroid plexus of the lateral ventricle were both common on the left side of 56%. Earlier studies of the brain by other methods have also shown asymmetry. An awareness of these anatomic asymmetries in normal individuals should preclude the erroneous diagnosis of an atropic or mass lesion.

Adolescent↗

An evaluation of the Coulter Diff3 50, an automated differential leukocyte counter.

The Coulter Diff3 50 analyzes Wright stained films using computerized pattern recognition. It is capable of reporting on the differential leukocyte count, red cell morphology, platelet sufficiency and the reticulocyte count. Although the precision of the differential leukocyte and reticulocyte counts is better than that of the manual method, correlation is poor and monocyte classification is a major problem. The Diff3 50 is useful for examining relatively normal films and for follow-up counts, but in our experience it has proven more unreliable and costly than expected.

Basophils↗

Minimal deviation hepatoma. A new entity.

The term minimal deviation hepatoma has been applied to a specific clinical, pathological, and angiographic entity. It is a tumor, composed of atypical cells, which is neither frankly malignant nor so well organized as a benigh tumor. This lesion occurs in females with otherwise normal livers and has a relatively benign course, although life threatening hemorrhage may occur. The diagnosis may be strongly suggested in the presence of hypervascularl or hypovascular discrete masses without evidence of frank malignancy, with a defect in the colloid liver scan and with normal liver function tests. Surgical resection when possible and aggressive chemotherapy may be corrective in many cases.

Adult↗

Sickle-cell anemia--a review.

Sickle-cell anemia is a common disease, affecting more than 50,000 blacks in the United States. Since 1970 the morbidity and mortality have improved, with patients surviving well into their fourth decade. This article discusses the spectrum of serious complications of sickle-cell anemia. Crises and complications that result from the sickling process are presented with recommendations for emergency department evaluation and management. The painful bone crisis and pain control are also discussed.

Anemia, Sickle Cell↗