Biomedical subjects

S J Garber

Publications and source records attributed to S J Garber.

5 recordsLinked to original sources

PubMed1992

The characterization of pancreatic and bile duct tumours by duplex Doppler.

Duplex Doppler imaging was used to study the effect of pancreatic and bile duct tumours on portal vein and hepatic artery blood flow and the specific Doppler signals recorded from these tumours. Chaotic portal vein flow occurred in 35% (14) of pancreatic and 20% (6) of biliary tumours and complete portal vein occlusion in 28% (11) and 10% (3) respectively. Twenty-eight per cent (11) of pancreatic and 7% (2) of bile duct tumours had high frequency shift Doppler signals and 22% (9) of pancreatic tumours had a signal indicating low impedence flow. Both signal types are suggestive of malignancy. The results suggest that pulsed Doppler imaging has a valuable place in the ultrasound assessment of portal vein wall invasion, is an important staging criterion for pancreatic and biliary tumours and may assist in differentiating benign from malignant lesions.

Aged↗

PubMed1992

Enlarged mediastinal lymph nodes in the fibrosing alveolitis of systemic sclerosis.

The aim of this study was to determine the prevalence of enlarged mediastinal lymph nodes in systemic sclerosis (SSc) and relate this to the extent of pulmonary disease and disease activity as judged by high resolution computed tomography (HRCT). The HRCT scans of 78 patients with SSc were reviewed. The extent of lung disease and HRCT pattern were analysed and CT scans examined on soft tissue window settings for evidence of mediastinal lymph node enlargement. Sixty six (85%) patients had evidence of lung involvement on CT. Enlarged mediastinal lymph nodes were present in 21 (32%) patients with lung involvement but in only 1 (8%) patient without. The prevalence of enlarged mediastinal nodes increased with more extensive lung involvement on CT (p < 0.025), but correlated poorly with the type of CT appearance and concurrent erythrocyte sedimentation rate. Mediastinal lymph node enlargement occurs frequently in patients with SSc, particularly if lung involvement is extensive.

Adult↗

PubMed1991

Case report: the ultrasound and computed tomography appearance of mesenteric Castleman disease.

Castleman disease is a rare, benign disorder characterized by proliferation of lymphoid tissue most commonly presenting as a solitary mediastinal mass. We discuss the radiological findings in a 10-year-old female child with a mesenteric Castleman tumour presenting with intermittent abdominal pain and a persistently elevated erythrocyte sedimentation rate (ESR).

Castleman Disease↗

PubMed1991

Laurence-Moon-Biedl syndrome: renal ultrasound appearances in the neonate.

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Adult↗

PubMed1990

Voiding dysfunction due to neurosyphilis.

Three patients with neurosyphilis presenting with urinary frequency, incontinence and voiding dysfunction were investigated. Unlike the previously reported finding of areflexia in tabes dorsalis, all 3 had hypocompliant detrusor hyper-reflexia with detrusor-sphincter dyssynergia and post-micturition residual urine. One patient also had bladder neck dyssynergia treated by bladder neck incision. The other 2 patients were initially managed by intermittent catheterisation but 1 ultimately underwent urinary diversion. The clinical relevance of these findings and the treatment of this condition are discussed.

Aged↗