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Biomedical subjects

S J McCabe

Publications and source records attributed to S J McCabe.

26 records · Page 2Linked to original sources

The measurement of cold sensitivity of the hand.

There is no widely accepted method of measuring the severity of cold sensitivity of the hand. A patient-answered questionnaire was developed. This consisted of seven items divided into two subscales: the first to measure the severity of cold sensitivity, and the second to grade exposure of the hands to cold at the workplace. The test-retest reliability was 0.92 for the severity subscale and 0.94 for the work exposure scale. An initial test of validity supports the use of the scale to measure cold sensitivity of the hand.

Adult↗

Replantation.

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Amputation, Traumatic↗

Haemangioma of the digital nerve: a case report.

An intra-neural haemangioma of the digital nerve of the left index finger is described, the first report of such a lesion in a digit. Treatment consisted of excision of the tumour and the affected portion of the nerve, followed by direct coaptation of the nerve ends.

Adult↗

A case of neurofibroma of the palmar cutaneous branch of the median nerve.

This case report describes a previously unreported entity, a neurofibroma of the palmar cutaneous branch of the median nerve. The lesion presented as a palmar mass with an overlying abnormality of the skin. Treatment consisted of excision of the lesion. Infiltration of the terminal branches of the nerve by the tumour prevented nerve reconstruction but provided a previously unknown diagnostic clue: fibrosis of an area of skin innervated by the involved nerve, which had the appearance of a callosity.

Adult↗

The nerve of Henlé.

The nerve of Henlé, a branch of the ulnar nerve in the forearm, is thought to deliver sympathetic innervation to the ulnar artery. Forty cadaver forearms were dissected under magnification. Two distinct patterns of the nerve were found. In the typical pattern, 18 (45%) of 40 extremities, the nerve originates 16 cm proximal to the ulnar styloid, travels distally with the ulnar artery, and frequently, 13 (72%) of 18, branches to pierce the superficial fascia 6 cm proximal to the ulnar styloid and innervate the skin of the distal ulnar forearm. In the atypical pattern (12%), the nerve originates in the distal 8 cm of the forearm and travels briefly with the ulnar artery before branching to the skin. The palmar cutaneous branch of the ulnar nerve was absent in cadavers with the nerve of Henlé and may be a distal variant of that nerve.

Arteries↗

A technique for replantation of the finger tip.

The finger-tip replantation technique reported here has evolved over 15 years. Indications for surgery include both strong patient desire and specialized use of the finger tip. Palmar flaps are elevated as full-thickness skin grafts to avoid injury to palmar veins. Arteries and palmar digital veins are repaired using an open-vessel technique. Postoperative care varies from immediate discharge with follow-up to inpatient care using surgical leeches or continuous bleeding as a method of drainage should venous congestion develop. The survival rate of 26 finger tips replanted using this technique between 1981 and 1987 was 69%. Two-point discrimination returned in 75% of patients, and 25% had two-point discrimination of less than 5 mm. The distal interphalangeal joint retained an average range of motion of 56 degrees. Appearance was excellent, and patient satisfaction was high.

Fingers↗

Vascular isolation of the rat cremaster muscle.

The vascular supply to the rat cremaster muscle was completely isolated to provide a microvascular preparation with a controllable blood flow. The anatomy of the cremaster vascular supply and the surgical approach to isolate the cremaster muscle on its neurovascular pedicle are described. The functional integrity of this isolated cremaster preparation was tested using intravital video microscopy to evaluate the tissue's response to vasoactive agents and to peripheral nerve stimulation. The isolated cremaster muscle was positioned in situ in a controlled tissue bath and concentration response curves to the topical application of norepinephrine (NE) and acetylcholine (Ach) were determined. Vasoconstriction elicited by the topical application of NE or by stimulation of the genitofemoral nerve trunk was similar for both the isolated and standard cremaster preparations. Application of 10(-5) M Ach caused maximal vasodilation equal to that produced by 10(-3) M papaverine in both preparations. In summary, the isolated cremaster muscle of the rat is an acceptable model of a skeletal muscle microcirculation which can be used to investigate microvascular function when precise monitoring or control of perfusion to the entire muscle is needed.

Acetylcholine↗

Mycoplasma infection of the hand acquired from a cat.

Mycoplasmas, the smallest known organism capable of a free existence, have been recognized as human pathogens for 25 years. However, a soft tissue cellulitis caused by a mycoplasma has never been reported in a human subject. This case report of a mycoplasma infection of the hand acquired from an infected cat describes the clinical presentation, operative findings, mycoplasmology, and treatment of this infection.

Adult↗