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Biomedical subjects

S J Pak

Publications and source records attributed to S J Pak.

5 recordsLinked to original sources
PubMed2001

[RecDate - an IT-solution for the documentation and quality management of reproductive medicine].

OBJECTIVES: The aim of this paper was to describe the possible use of the software RecDate für documentation and Quality Management in Reproductive Medicine. MATERIAL AND METHODS: RecDate was programmed using the data base program Filemaker Pro. The functions and potentials of RecDate were analyzed. RESULTS: RecDate enables the collection, documentation and evaluation of data from Reproductive Medicine and also functions as a hospital management tool. CONCLUSIONS: The present status of Reproductive Medicine can be described by the use of RecDate in IVF-clinics, which is important for consulting and treatment of couples, for the quality of public enlightenment and for optimizing the processes in daily routine.

Computer Communication Networks↗
PubMed1999

LETM1, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients.

Deletions within human chromosome 4p16.3 cause Wolf-Hirschhorn syndrome (WHS), which is characterized by severe mental and developmental defects. It is thought that haploinsufficiency of more than one gene contributes to the complex phenotype. We have cloned and characterized a novel gene (LETM1) that is deleted in nearly all WHS patients. LETM1 encodes a putative member of the EF-hand family of Ca(2+)-binding proteins. The protein contains two EF-hands, a transmembrane domain, a leucine zipper, and several coiled-coil domains. On the basis of its possible Ca(2+)-binding property and involvement in Ca(2+) signaling and/or homeostasis, we propose that haploinsufficiency of LETM1 may contribute to the neuromuscular features of WHS patients.

Amino Acid Sequence↗
PubMedDate not supplied

Treatment of multiple bilateral juvenile fibroadenomas in a teenage breast by central pedicle breast reduction, with vertical and short horizontal scar: case report.

An 11-year-old girl presented with extremely large and slightly asymmetric breasts that had developed over a 1-year period. The condition was diagnosed as multiple bilateral juvenile fibroadenomas on the operative field and successfully treated with central pedicle breast reduction using a vertical and short horizontal scar design. Breast function and aesthetic appearance were preserved with no reported recurrence 5 years after surgery.

Breast Neoplasms↗