Anicteric hepatitis in an adult associated with coxsackie b4 virus infection.
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Biomedical subjects
Publications and source records attributed to S Jankovic.
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OBJECTIVE: The purpose of this study is to evaluate peripheral nerve war injuries sustained during the war in southern Croatia and Bosnia and Herzegovina. PATIENTS AND METHODS: During the war in Croatia, 713 patients (99% male and 1% female) with wounds inflicted by firearms were examined at the Laboratory of Neurophysiology, University Hospital, Split. The patients, soldiers and civilians alike, ranged in age from 6 to 73 years (average, 28 years). All patients with firearm nerve war injuries underwent detection by electromyography and plurisegmental examination of the damaged peripheral nerve (neurography). The patients were examined and controlled on three occasions: within 2 months after wounding; up to 6 months after wounding; and more than 6 months after wounding. RESULTS: Single peripheral nerve lesions were present in 80% of the patients, and multiple peripheral nerve or plexus lesions were present in 20% of the patients. Peroneal and ulnar nerves were most often involved (20.9% and 19.8%, respectively). Associated massive injuries to the muscles, large blood vessels, or vital organs were present in 45% of the patients. Wounds were inflicted by shell fragments in 80% of the patients and by projectiles in 20% of the patients. CONCLUSION: According to our results, better recovery was achieved with conservative treatment and when physical therapy was initiated early with maximal patient cooperation. Electromyoneurographic findings were the most valid in the prognostic classification of war-inflicted peripheral nerve injuries.
The effect of vasopressin and oxytocin on the contractile activity of preparations isolated from the feline gastric corpus wall was investigated. Vasopressin (1.5 x 10(-9)-2.1 x 10(-7) M), but not oxytocin, evoked concentration-dependent tonic contractions only of longitudinal muscle strips. At the same time, vasopressin (1.5 x 10(-9)-2.1 x 10(-7) M) potentiated the magnitude of amplitudes, but not the frequency, of spontaneous contractions. Both the vasopressin V1 receptor antagonist d(CH2)5-(Me)2-Tyr-AVP and the predominantly vasopressin V2 receptor antagonist d(CH2)5, D-Ile2, Ile4-AVP, the non-selective muscarinic receptor antagonist, atropine, the predominantly selective muscarinic M1 receptor antagonist, pirenzepine, the predominantly selective muscarinic M2 antagonist, methoctramine, the predominantly selective muscarinic M3 receptor antagonist, para-fluoro-hexahydro-siladifenidol, and the calcium channel blocker, nifedipine, but not the ganglion blocking agent, mecamylamine, depressed or blocked the tonic contractions induced by vasopressin. Among the antagonists, only atropine and nifedipine inhibited the spontaneous contractions. On the other hand, the anticholinesterase, physostigmine, potentiated both the vasopressin-induced tonic and spontaneous contractions. With regard to the receptors, the vasopressin-induced tonic contractions are mediated at least in part through vasopressin V1 and V2 receptors, non-selective muscarinic and selective muscarinic M1, M2 and M3 receptors. The increase in amplitudes of spontaneous contractions is mediated only via-nonselective muscarinic receptors. Vasopressin receptors appear to be located mostly pre-synaptically, although the direct effect of vasopressin on post-synaptic receptors cannot be excluded. The pA2 values suggests rather V1a than V1b vasopressin receptor subtype involvement in tonic contractions vasopressin had produced. The tonic as well as spontaneous contractions are calcium-dependent. In addition, these results point to the existence of non-selective muscarinic receptors, which participate in the regulation of both tonic and spontaneous contractions, while muscarinic M1, M2 and M3 receptors subserve only the tonic contractions.
Rhinosporidiosis occurs extremely seldom in Europe. Until recently, the disease was unknown in Serbia (Yugoslavia). An outbreak that began in January 1992, affected 21 individuals. All of them had been exposed to the same source of stagnant water. The purpose of this study was to assess which control measures would be selected by epidemiologists potentially involved in the control of the disease. Most respondents (20 of 32 or 62.5%) opted only for an information release as the most appropriate control measure. The reasons listed by the epidemiologists to justify their choice of optimal control measures showed that the political and economic hardships, including an embargo imposed upon rump Yugoslavia, did not hamper their judgment. The turmoil associated with the disintegration of Yugoslavia, however, appears to have significantly affected the information level of the participants.
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A case-control study of 130 patients with chronic lymphocytic leukemia (CLL) and 130 controls matched with respect to sex, age (2 years), type of residence (urban-rural) and area of residence (according to the national per capita income) was carried out. Conditional logistic regression analysis showed that, apart of four risk factors already described in the literature (work in a hazardous industry, hair dye use, family history of leukemia and exposure to electromagnetic radiation), brick mortar exposure was also significantly related to CLL.
A case-control study comprised 130 cases affected by chronic lymphocytic leukemia and the same number of individually matched controls, with accidental injuries as a cause of hospitalization. Matching criteria were: sex, age, type of settlement, and area of residence. Both leukemias and all cancers were more frequent among family members of cases, as compared to controls.
A total of 366 inhabitants of a village affected by Balkan nephropathy (BN) have been followed over 12 years. It was shown that depth of the well to the water level, height of the water column, electroconductivity, and NO3 content of the water were not associated with BN. The risk of developing the disease was significantly higher if a well was at a lower altitude and contained a higher concentration of SiO2. Low altitude might have been expected to correlate with the BN frequency; as for silica, however, there are sound indications that it could just be a correlate of a cause rather than a direct determinant of BN.
We describe a patient with Takayasu's arteritis (type I): occlusion of all large vessels of the aortic arch except the left subclavian artery which was, however, almost completely occluded, resulting in a characteristic subclavian steal syndrome. Elective left main subclavian artery balloon angioplasty followed by endoluminal stenting was performed with excellent results. After prolonged immunosuppressive treatment, at the 12-month follow-up there was no evidence of restenosis. In selected patients with Takayasu's arteritis and subclavian stenosis, elective endoluminal stenting can be used as a definitive procedure or as a bridge to surgical revascularization.
INTRODUCTION AND METHOD: A retrospective study was made of the incidence of stroke in the Dalmatian region (Split) during the war in the Republic of Croatia (1991-1995), to determine whether the war had affected the incidence of stroke in the population at risk. The data obtained was compared with data regarding the incidence of strokes in the pre-war period (1986-1990). RESULTS AND CONCLUSIONS: There was a small but significant increase in the incidence of strokes during the war period. There was also a considerable increase in patients with primary intracerebral hemorrhage during this period. The possible causes of this increase in patients with primary intracerebral hemorrhage are discussed.
A matched case control study was conducted in order to assess possible relationships between some habits and risk of bladder cancer. The study included 130 newly diagnosed bladder cancer patients and the same number of controls matched with respect to sex, age (+/- 2 years) and type of residence (rural-urban). According to multivariate logistic regression analysis, risk factors of bladder cancer were smoking habits (OR = 3.15), consumption of animal fats (RR = 2.10) and pickled food (RR = 21.28). Higher level of educational (RR = 0.51), frequent urination (RR = 0.21), consumption of greens (RR = 0.10), cherry (RR = 0.03) and tangerines (RR = 0.02) had a protective effect.