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S Jarpa

Publications and source records attributed to S Jarpa.

At least 19 recordsLinked to original sources
PubMed1986

Urinary kallikrein excretion in pregnant adrenalectomized rats.

The mechanisms responsible for the increase of the urinary kallikrein activity (UKA) during pregnancy is still unknown. Since aldosterone has been described as one of the stimulatory factor of UKA, and this hormone is considerably elevated in normal pregnancy it is feasible to postulate that it might be involved in the process. A preliminary approach to solve the role of the mineralocorticoid was to investigate the effect of the adrenalectomy upon UKA, of pregnant rats. UKA activity and blood pressure (BP) were measured at weekly intervals in four groups of rats: pregnant-adrenalectomized (P-ADX); pregnant-sham operated (P-C); non pregnant-adrenalectomized (NP-ADX) and non pregnant-sham operated (NP-C). In addition serum aldosterone levels in pregnant rats were determined. All the groups were maintained in similar conditions drinking 1% NaCl solution. The increase in UKA was not detected in P-C, as observed in normal pregnant rats drinking tap water, indicating that a high NaCl intake prevents the rise in UKA during gestation. However, P-C rats had higher UKA than P-ADX on day 14 of pregnancy (p < 0,05). The lowest level of UKA was found in NP-ADX. In NP-C and NP-ADX BP rose progressively throughout the experiment. BP in P-ADX rats during pregnancy and on day 7 of post partum was significantly lower than in P-C rats (p < 0,01-0,02) but in both pregnant groups it decreased significantly before parturition (p < 0,02) increasing at post-partum. Serum aldosterone levels on days 14 ans 21 of gestation, showed higher values in P-C than in P-ADX (p < 0,02-0,005). The results provide support to the assumption that adrenal gland has a regulatory action on UKA during pregnancy and that aldosterone can be one of the main factors involved.

Adrenal Cortex↗
PubMedDate not supplied

Colonic stomas.

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Cecum↗
PubMedDate not supplied

[A new cow's milk formula to Complementary Feeding National Program: nitrogen and caloric balance].

Nitrogen, fat and energy retention were measured in 10 male infants (mean age = 6.8 mo) recovering from marasmic malnutrition while they were fed with either cow's milk based formula (LP) or a modified cow's milk formula (LPM). Their mean weight for age ratio was 72% and their weight for length ratio was 95% (NCHS standards). They went through two consecutive balance periods of 6 days each (3 d. for adaptation and 3 d. for urine and feces collection) beginning with either formula randomly. Both formulas had 85 kcal/dl with 11% protein calories in LPM and 13% in LP. Energy intake, absorption and relative retention were slightly greater with LPM than LP. Fat intake was greater under LPM than LP (5.4 vs. 4.5 g-kg-d, p < 0.025), which resulted in significant differences in fat absorption (LPM 4.3 vs. LP 3 g-kg-d, p < 0.025). Nitrogen intake was significantly lower under LPM than LP (487 vs. 571 mg-kg-d, p < 0.025) with lower urinary nitrogen excretion for LPM than for LP (304 vs. 417 mg-kg-d, p < 0.001). Apparent nitrogen retention averaged 115 mg-kg-d for LPM and only 69 mg-kg-d for LP (NS). A significant correlation was observed between nitrogen intake and nitrogen retention: r = 0.70 (y = 0.57x -167; p < 0.05) with LPM, and r = 0.77 (y = 0.63x -291, p < 0.01) with LP. A correlation was also found between energy intake and weight gain: r = 0.55 (NS) with LPM, and r = 0.88 (y = 0.26x -26; p < 0.001) with LP.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗