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Biomedical subjects

S Johannessen

Publications and source records attributed to S Johannessen.

9 recordsLinked to original sources
PubMed1992

How does computer-aided diagnosis improve the management of acute abdominal pain?

The introduction of standardised data-collection forms and computer-aided diagnosis has been found to be associated with improved diagnosis and management of patients with acute abdominal pain. The mechanism by which such benefits accrue has been the subject of some controversy. Detailed analysis of 5193 patients from one hospital shows that the major benefit from such diagnostic aids was the accurate early diagnosis of non-specific abdominal pain by senior house officers in the accident and emergency department; this in turn led to fewer admissions and fewer operations with negative findings. Clinical data about patients with acute abdominal pain should be recorded on structured information sheets by junior doctors and early positive diagnosis should be encouraged before decisions affecting the patient's management are made. Improved computer support may confer further benefits.

Abdomen, Acute↗
PubMed1984

Reproducibility of radiographs with the orthopantomograph 5: tooth-length assessment.

The precision of tooth-length assessments based on repeated panoramic radiographs made with a Siemens OP 5 was investigated in three groups of twenty patients. Two exposures of the same patient were made under three different radiographic conditions. Of the tooth lengths, nonmeasurability was found in 14% to 17%. The variability (standard deviation) of the measurements assessed from repeated radiographs ranged from 0.65 to 0.85 mm, or 2.4% to 3.1% of the mean radiographic tooth length in the different patient groups. The measurement error ranged from 0.43 to 0.56 mm, indicating that the main source of error inherent in the method was recognition of the reference points. Small differences were found between the tooth groups and between the right and left sides.

Adolescent↗
PubMed1977

Evaluation of a new immunoassay for determination of phenytoin and phenobarbital: results of a European collaborative control study.

The performance of a new enzyme multiplied immunoassay technique (EMIT) was compared with other current methods, namely gas-liquid chromatography and thin-layer chromatography, for the determination of phenytoin and phenobarbital in serum. Forty-three serum samples were sent as unknowns to the participating laboratories for determination. The precision of repeated determinations was very similar for EMIT and chromatography. There was good agreement among gas chromatography, thin-layer chromatography, and EMIT results. Interlaboratory variability was lower for EMIT determinations of both antiepileptic drugs. The rapid analysis of small samples, made possible by the EMIT system, could have beneficial effects on the treatment of epilepsies.

Chromatography, Gas↗
PubMed1977

Interlaboratory variability of valproic acid determinations.

19 pooled plasma specimens were sent as unknowns to 13 participating research laboratories. The interlaboratory variability between the results was very high. Only 4 out of 13 laboratories had 6--12% of their results within the 95% confidence limit for each sample. The precision of repeated determinations was fairly good. 6 out of 10 participating laboratories had a coefficient of variation of less then 5%. The reproducibility and the agreement between the different procedures for quantitative analysis of dipropylacetate is similar to that reported for other major antiepileptic drugs.

Laboratories↗
PubMedDate not supplied

Transpharyngeal radiography of mandibular condyle. Comparison with other conventional methods.

Transpharyngeal examination of the mandibular condyle was compared with transcranial and transmaxillary examinations in 22 patients with mandibular pain/dysfunction. All projections were supplementary and a combination of at least two methods seemed preferable. When a single examination was used, underestimation of abnormalities was evident. In demonstrating condylar destruction, the transpharyngeal examination seemed to be superior to the more commonly used transcranial, but inferior to the transmaxillary examination.

Adolescent↗