5-Fluorouracil as adjuvant chemotherapy for large bowel cancer. Is it appropriate for routine community use?
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BCG Vaccine↗
Biomedical subjects
S K Carter
Publications and source records attributed to S K Carter.
Methodology of data reporting in advanced breast cancer trials.
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Breast Neoplasms↗
A perspective on adjuvant chemotherapy of testicular cancer.
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Antineoplastic Agents↗
Experimental design considerations in clinically combining radiation and drugs.
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Antineoplastic Agents↗
C.R.O.S. conference on combined modalities chemotherapy/radiotherapy. Hilton Head Island, South Carolina, November 15--18, 1978.
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Antineoplastic Agents↗
Anthracycline analogs: re-assessments and prospects.
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Animals↗
The dilemma of estrogen receptors and the response rate to cytotoxic chemotherapy. A problem of comparability analysis.
The question of whether estrogen receptor assay predicts for chemotherapy response and, if so, how, is currently controversial. Two papers have recently appeared with widely differing results. Both papers use retrospective analysis and are so heterogeneous as regards assay criteria for positivity, prognostic variable and drugs used that they cannot in truth be meaningfully compared. Resolution of the question will probably have to await prospectively designed trials.
Antineoplastic Agents↗
Second tumors complicating cancer chemotherapy.
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Alkylating Agents↗
Concluding remarks on malignant lymphomas.
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Antineoplastic Agents↗
The clinical evaluation of analogues II. Bleomycins.
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Bleomycin↗
Cancer chemotherapy as it approaches middle age.
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Antineoplastic Agents↗
New drugs under clinical evaluation in the United States.
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Aldehydes↗
The clinical evaluation of analogues. I. The overall problem.
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Antineoplastic Agents↗
Adjuvant chemotherapy in breast cancer: critique and perspectives.
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Breast Neoplasms↗
NCI-EORTC symposium on new drugs in cancer therapy. Brussels, Belgium, September 7--8, 1978.
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Antineoplastic Agents↗
The analysis of adjuvant trials.
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Antineoplastic Agents↗
Chemotherapy and genitourinary oncology. I. Bladder cancer.
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Aged↗
Management of trials in the development of cancer chemotherapy.
Potential anti-cancer agents have classically undergone clinical assessment in Phase I, II and III trials. This paper examines the role of these trials and pre-clinical studies in the light of improving cancer chemotherapy. Many patients must now be treated with standard therapy before investigational drugs can be ethically used. The introduction of combined modality trials will require a very prolonged follow-up to demonstrate improved survival and recognize late onset of chronic toxicity.
Animals↗