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Biomedical subjects

S K Chaudhary

Publications and source records attributed to S K Chaudhary.

At least 19 recordsLinked to original sources
PubMed1988

Sequential pathological studies in Japanese quails infected experimentally with Aspergillus fumigatus.

Intratracheal inoculation of young quail chicks with Aspergillus fumigatus spores resulted in the development of characteristic gross and microscopic lesions. The lesions were restricted to respiratory tract and there was no dissemination of infection to other tissues of the body. Gross changes in lungs and air sacs were observed within 24 hours and continued up to 20 days while in trachea these were noticed from the 3rd to the 9th day post-infection. The lesions, in general, included congestion and focal haemorrhages in the first 2 days followed by the development of varying-sized greyish-white nodules in the lungs, air sacs and trachea. Microscopic changes consisted of congestion, haemorrhages and a diffuse cellular infiltration in the first 2 days followed by granulomatous reaction with well developed granulomas in lungs, air sacs and trachea. Spores and developing hyphae of Aspergillus could be demonstrated in sections from 24 hours to 20 days of infection. Reisolation of the fungus was consistently achieved from the lungs, air sacs and trachea up to 14 days.

Air Sacs↗
PubMed1988

Experimental aspergillosis in Japanese quails (Coturnix coturnix japonica). Clinical signs and haematological changes.

Intratracheal inoculation of 2-week-old quail chicks with Aspergillus fumigatus resulted in the development of clinical signs within 24 h of infection. These were characterized by anorexia, depression, accelerated respiration and gasping followed by death. The acute course of the disease lasted for 7-10 days followed by recovery in the surviving chicks. The overall mortality during a 6-week observation period was 20%. Although the mean body weight of A. fumigatus infected quail chicks continued to be slightly lower throughout the experiment but the difference, in comparison to controls, was not significant except at 42 days post-infection. There was no appreciable difference in the mean values of Hb, TEC, PCV, MCV, MCH and MCHC between the infected and control chicks at any stage of infection but TLC revealed a leucocytosis from 2-7 days which was the result of increase in the relative percentage of heterophils and decrease in lymphocytes.

Animals↗