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S K Lekh

Publications and source records attributed to S K Lekh.

6 recordsLinked to original sources
PubMed2001

SPECT neuroimaging in schizophrenia with religious delusions.

Functional neuroimaging techniques such as single-positron emission computed tomography (SPECT) and positron emission tomography (PET) offer considerable scope for investigating disturbances of brain activity in psychiatric disorders. However, the heterogeneous nature of disorders such as schizophrenia limits the value of studies that group patients under this global label. Some have addressed this problem by considering schizophrenia at a syndromal level, but so far, few have focussed at the level of individual symptoms. We describe the first neuroimaging study of the specific symptom of religious delusions in schizophrenia. 99mTc HMPAO high-resolution SPECT neuroimaging showed an association of religious delusions with left temporal overactivation and reduced occipital uptake, particularly on the left.

Adult↗
PubMed2000

A comparison of patients admitted to two medium secure units, one for those of normal intelligence and one for those with learning disability.

Differences between patients being treated in two different medium secure units, one for those of normal intelligence and one for those with learning disability, were investigated. Sociodemographic, psychiatric, medical and medicolegal data were recorded for all inpatients in both secure units. Patients in the medium secure unit for those of normal intelligence were older at the time of the study and at conviction for the index offence, more likely to have been admitted from the penal system, and more likely to suffer from a psychotic disorder, particularly schizophrenia or a mood disorder. Their index offence was more likely to be homicide, attempted murder, manslaughter or grievous bodily harm, while that of the patients with learning disability was more likely to be a sexual offence. A need for separate medium secure unit facilities for those of normal intelligence and those with learning disability is supported by differing psychiatric and behavioural requirements.

Adult↗
PubMed1995

Mortality in a hospitalized mentally handicapped population: a 10-year survey.

The mortality experiences of a hospitalized mentally handicapped population between 1981 and 1990 (inclusive) were examined. A continued trend for increasing longevity in both males and females was found, with mean ages at death now approaching those in the general population. The commonest cause of death was non-tubercular respiratory infection, from which patients were particularly at risk during the months of December to February (inclusive). Patients diagnosed as suffering from psychoses other than schizophrenia and mood disorder had an increased mortality and should be thoroughly investigated for the presence of organic pathology. Epilepsy and Down's syndrome were associated with increased risk of earlier death, although in the case of Down's syndrome there has been a marked increase in longevity.

Adult↗
PubMedDate not supplied

Social drift in forensic psychiatric inpatients with schizophrenia.

The highest social class before admission of 27 forensic psychiatric inpatients in a regional secure unit who suffered from schizophrenia was found to be significantly lower than that of their fathers. This is the first report of social drift in this group of patients.

Adult↗