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Biomedical subjects

S K Marya

Publications and source records attributed to S K Marya.

At least 19 recordsLinked to original sources

Comparative evaluation of fine needle aspiration cytology and biopsy of testis in diagnosis of male infertility.

Infertility has a fair degree of male factor contribution in its aetiology, hence needs complete evaluation of male partner especially the status of spermatogenesis. In the present study comparative evaluation of fine needle aspiration cytology (FNAC) and biopsy of testis showed 90% accuracy of FNAC in respect of histopathological diagnosis of spermatogenesis. FNAC is a safe, fairly accurate, outdoor investigation in infertile man and it is devoid of the complications of haematoma formation, suppression of spermatogenesis and antigenic stimulation as seen with testicular biopsy.

Adult↗

Allograft in the treatment of benign cystic lesions of bone.

Seventeen patients with benign cystic osseous lesions were treated by curettage and grafting using allogenic decalcified bone. Human bones were partially decalcified using 0.6 N HCl and preserved in 90% ethanol in a deep freezer at -16 degrees C. The cystic lesions were: 5 cases of fibrous dysplasia, 4 aneurysmal bone cysts, 3 simple bone cysts, 2 giant-cell tumours, 1 chondromyxoid fibroma, 1 non-ossifying fibroma and 1 fibrous cortical defect. The bones involved were: femur, tibia, humerus, fibula and calcaneum. Infection was a complication in three patients. In two of these it did not interfere with healing, but in one it persisted for more than 1 year with partial resorption of the graft. The time to adequate incorporation of the graft varied from 6 to 9 months in children and 9 to 15 months in adults. The overall response compares favourably with that to allograft from more sophisticated bone banks.

Adolescent↗

Is a long delay necessary before appendectomy after appendiceal mass formation? A preliminary report.

The standard treatment for an appendiceal mass is conservative therapy followed by appendectomy after 6 to 10 weeks. With the advent of antibiotics designed to prevent the growth of anaerobes, early appendectomy can now be carried out without complication. The authors studied 56 patients with appendiceal mass formation, 26 (group A) treated conventionally and 30 (group B) treated by early appendectomy. In group B, the infection rate was 17%, the mean operating time was 38.7 minutes, the mean hospital stay was 15 days and there was an early return to work. The corresponding parameters for group A were an infection rate of 8%, a mean operating time of 35.2 minutes, a hospital stay of 19.1 days and a late return to work. Furthermore, 15% of the patients in group A had a recurrent acute episode during the waiting period. Overall, early appendectomy appears to be a safe and cost-effective treatment for appendiceal mass formation.

Abscess↗

Acute osteomyelitis: early diagnosis by ultrasonography.

A prospective study was carried out to evaluate the role of ultrasound in early detection of infections of bone. Presence of a hypoechoic collection adjacent to bone was considered highly suggestive of osteomyelitis whereas a hypoechoic collection away from the bone implied a soft tissue abscess. Cellulitis presented as increased subcutaneous thickness. Of the 31 patients clinically suspected to have osteomyelitis, and subjected to ultrasound, 25 were proven to be osteomyelitis at surgery or by subsequent radiological changes, 4 had soft tissue abscesses and the remaining 2 had cellulitis. Co-existent hip joint effusion was seen in 2 patients. It is felt that ultrasound is simple and non-invasive investigation, capable of detecting bone and soft tissue infections.

Acute Disease↗

Prediction of postoperative retention in elderly patients undergoing nonprostatic surgery by preoperative uroflowmetry.

500 patients above 50 years of age, undergoing lower abdominal/perineal surgery and having no urinary complaints were assessed by measuring the preoperative maximum flow rate (Qmax). They were subsequently observed for urinary retention in the postoperative period. The analysis of the results has shown a definite relation between the preoperative Qmax and the probability of urinary retention in the postoperative period and uroflowmetry has been found to be a good screening procedure for the detection of cases which could possibly have urinary trouble requiring significant intervention in the postoperative phase, thereby changing the priority of surgical attention.

Humans↗

Angiomyolipoma of kidney.

Angiomyolipoma is an uncommon benign tumour accounting for less than 1% of all surgically excised tumours of the kidney. It may present as an isolated lesion or in association with tuberous sclerosis. An impalpable tumour is often detected incidentally during investigation of a case for some urinary tract pathology. CT scan has proved to be a useful investigation for pre-operative diagnosis; it may however, be of no value if the fat content of the tumour is low. Here a case of angiomyolipoma of left kidney is reported where pre-operative diagnosis was suggested by CT scan and histopathology confirmed it.

Female↗

Maximum flow rate-guided dilatation in patients of stricture urethra: a controlled study.

Maximum flow rate (MFR) is an objective uroflowmetric parameter for assessment of urethral stricture. Its use as a guide to assess the frequency of dilatation of the urethra on an outdoor basis could make the approach very scientific and objective. 70 cases were evaluated in two groups, study and control, each of 35 patients. Dilatation in the study group was guided by serial measurement of MFR, while in the control group, stricture was dilated on a traditional scale. A comparison between the two groups showed a statistically significant decline in the frequency of dilatation in the study group. A routine practice of MFR-guided dilatation in stricture clinics is recommended by us.

Adult↗

Intestinal malrotation in adults.

Intestinal malrotation presenting with abdominal problems are not common beyond the neonatal period. An adolescent or adult harboring this anomaly may suffer from delay in diagnosis and inappropriate treatment including surgery. We report three patients, aged 17, 31 and 50 years, with intestinal malrotation presenting as an appendicular problem (2) and chronic abdominal pain (1). The former mode of presentation has not been reported so far.

Abscess↗