Biomedical subjects

S K Mattoo

Publications and source records attributed to S K Mattoo.

22 records · Page 2Linked to original sources

PubMed1992

Cases of buprenorphine abuse in India.

Buprenorphine was introduced as a potent analgesic with low abuse potential. Reports of buprenorphine abuse by opiate abusers have accumulated over the years, highlighting its use as a cheap alternative to heroin. The lower potency compared with heroin is being compensated by using a cocktail of buprenorphine with benzodiazepines or cyclizine. This study of 18 cases seen over 3 years broadly confirms these findings. Four cases reported haematemesis during acute withdrawal, a symptom not reported in earlier studies.

Adult↗

PubMed1989

Negative and depressive symptoms in schizophrenia.

Ninety-five schizophrenic patients were assessed using the Present State Examination, the Brief Psychiatric Rating Scale and the Scale for the Assessment of Negative Symptoms. Negative and depressive symptoms were frequent, and significant relationships among negative symptom complexes and depressive syndromes were noted. Retardation, lack of energy, slowness, and other symptoms of depression were significantly associated with the negative symptoms of schizophrenia. Depressed affect per se did not have a significant correlation with negative symptoms.

Defense Mechanisms↗

PubMed1986

Diagnostic systems for schizophrenia. A cross-sectional study of concordance from India.

In a cross-sectional study, five diagnostic systems for schizophrenia: CATEGO, Research Diagnostic Criteria, DSM-III, Feighner's Criteria, and Schneider's First Rank Symptoms, were evaluated for their usefulness, comprehensiveness and concordance, using a clinical diagnosis conforming to the ICD-9 concept of schizophrenia. The sample consisted of 112 patients. It was found that all the diagnostic systems had good agreement with the index diagnosis. The rate of concordance among the systems varied. The advantages and limitations of each system and its usefulness in Indian context are discussed.

Acute Disease↗

PubMedDate not supplied

Correlates of early- and late-onset alcohol dependence.

The present study aimed at finding out demographic, clinical, personality, and behavioural correlates of age at onset of alcohol dependence. Fifty-one male patients of alcohol dependence (DSM-III-R, APA, 1987) attending the drug de-addiction clinic of a general teaching hospital in India comprised the sample. They were administered a composite socio-demographic and alcohol use proforma, modified Sensation-Seeking Scale (SSS), Multiphasic Personality Questionnaire (MPQ), and a checklist of behavioural tendencies when drinking. The early-onset alcoholics (age at onset of alcohol dependence 25 years or less) were younger. They had a larger proportion of first-degree relatives with both lifetime use and abuse/dependence of alcohol but not of other psychoactive substances. They had experienced a greater number of alcohol-related problems in the previous 1 year. They were also higher sensation seekers, higher on the Psychopathic deviate scale of MPQ, and tended to display aggression, violence, and general disinhibition when drinking. The late-onset alcoholics (age at onset of alcohol dependence more than 25 years) were anxiety-prone and guilt-ridden, and had less alcohol-related problems. The two groups were comparable on duration, frequently, and quantity of alcohol consumption. The findings are discussed in relation to some of the recently proposed typologies of alcoholism.

Adult↗