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S K Pradhan

Publications and source records attributed to S K Pradhan.

8 recordsLinked to original sources
PubMed2006

Avian flu and possible human pandemic.

Avian flu is affecting the poultry animals world over since first outbreak in 1997 in Hong Kong and has resulted in 92 human deaths and culling of more than 150 million poultry animals in Asia and Europe. The loss to the economy has also been enormous. 13 new countries, including India, reported occurrence of the disease in poultry animals in February 2006 only, to the World Health Organisation. This rapid rate of spread of virus along with notoriety of the virus for frequent genetic re-assortment, which might enable H5N1 to infect human beings, threatens of possible influenza pandemic since the last pandemic in 1968. The human influenza caused by this subtype of the virus (H5N1) has high case fatality of 54% and majority of affected humans are between the age of 5 to 23 years. Lack of effective vaccine, poor knowledge about treatment, and with scarcity of public health measures in developing countries are major causes of concern. The real threat of impending pandemic can be avoided only if we act immediately on the basis of currently available source of information and apply scientific knowledge rationally for containment and prevention of bird flu and treat human cases promptly.

Animals↗
PubMed2006

Emergence of chikungunya virus in Indian subcontinent after 32 years: A review.

An outbreak of chikungunya virus is currently ongoing in many countries in Indian Ocean since January 2005. The current outbreak appears to be the most severe and one of the biggest outbreaks caused by this virus. India, where this virus was last reported in 1973, is also amongst affected countries. Chikungunya virus has affected millions of the people in Africa and Southeast Asia, since it was first reported in 1952 in Tanzania. Even then, natural history of this disease is not fully understood. The intra-outbreak studies, point towards recent changes in the viral genome facilitating the rapid spread and enhanced pathogenecity. The available published scientific literature on chikungunya virus was searched to understand the natural history of this disease, reasons for the current outbreak and the causes behind re-emergence of the virus in India. The paucity of the scientific information on various epidemiological aspects of chikungunya virus threatens off an epidemic as control of spread of virus might be difficult in the absence of appropriate knowledge. There is an immediate need of the research on chikungunya virus, for an effective vaccine besides strengthening the existing diagnostic laboratory facilities. The current outbreak can also be taken as a lesson for establishment of a system for continuous surveillance of diseases, considered disappeared from the countries. The re-emergence and epidemics are unpredictable phenomena but the impact of such events can be ameliorated by appropriate knowledge and by being in the right state of preparedness.

Aedes↗
PubMed2005

Primary signet-ring cell carcinoma mimicking segmental Crohn's colitis.

Primary signet-ring cell carcinoma of the colon is a rare entity with a dismal prognosis, mainly due to a delay in diagnosis. Here, we present a case of a 30-year-old Filipino woman who presented with symptoms mimicking inflammatory bowel disease. A barium enema and colonoscopy demonstrated a stricture in the rectosigmoid region. A biopsy revealed granulomatous changes indicative of inflammatory bowel disease. Despite initial improvement of her symptoms on total parenteral nutrition and steroids, the patient relapsed several weeks later with recurrent left lower quadrant pain. A subsequent biopsy revealed poorly differentiated signet-ring cell carcinoma of the colon. She was treated surgically with a left hemi-colectomy and primary repair. A high degree of suspicion is necessary to correctly diagnose these, often young, patients with primary signet-ring cell carcinoma early and have a positive impact on survival. The literature on primary signet-ring cell carcinoma is reviewed.

Abdominal Pain↗
PubMed2001

Effect of sewage water on the growth and yield parameters of wheat and blackgram with different fertilizer levels.

Impact of biologically treated domestic sewage water was studied on the growth and yield attributing characters of wheat and blackgram under different fertilizer levels in the field condition. There was no significant difference on the yield and yield attributing characters of wheat. However, yield attributing characters like number of tillers/plant, panicle length (cm), number of grains/panicle and 1,000 grain weight showed increasing trend to the tune of 13.29, 1.59. 5.49 and 3.79 per cent respectively over the tubewell irrigated crop. Yield was also increased to the tune of 3.63 per cent when the crop was irrigated with sewage water. Interactions between irrigation and fertilizer levels were also insignificant. However, sewage water with N60P45K45 responded better on tillering, panicle length, number of grains/panicle and yield of wheat. In case of blackgram, treated sewage water had no significant effect on the grwoth and yield attributing characters, rather sewage water had some negative effect on these parameters. Interactions between irrigation and fertilizer levels were insignificant. But tubewell irrigation with N10P10K10 was more responsive on growth parameters. When the crop was grown with tubewell irrigation and without fertilizer, yield attributing characters were more positively responded.

Agriculture↗