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Biomedical subjects

S Kadirov

Publications and source records attributed to S Kadirov.

4 recordsLinked to original sources

Cardiac inhibitory neurons in gastropod snail Achatina fulica.

Two inhibitory heart motor neurons (HI-1, HI-2) were identified in the visceral ganglion of the snail Achatina fulica. Both motor neurons were connected monosynaptically with the myocardium. Irregular action potentials composed a typical pattern of neuronal spontaneous electrical activity. The neurons shared common excitatory synaptic inputs, and were connected through electrical synapses. Neuronal endings of these cells responded to tactile stimulation and to cardiac stretching when the chemical synapses were blocked. HI-1 and HI-2 neurons both elicited inhibitory post synaptic potentials in the myocardium with a constant delay and thereby modulated cardiac spikes frequency and amplitude. Staining with the dye Lucifer yellow revealed that these two neurons were unipolar cells which had dendrites only in the visceral ganglion.

Action Potentials↗

Cardioexcitatory neurons in the snail Achatina fulica.

The excitatory motor unit of Achatina fulica is composed of five identified cardioregulatory motor neurons: three tonically active neurons (TAN-1, -2 and -3), a periodically oscillating neuron (PON) and a VG1 neuron. High frequency discharges in TAN neurons evoked slow depolarization waves. The PON elicited biphasic excitatory post synaptic potentials (EPSP). One spike in PON was sufficient to increase heart rate for several minutes. VG1 elicited discrete fast EPSP in the myocardium. Bursts of spikes from VG1 resulted in a summation of EPSP and transiently increased heart. VG1 inhibited spontaneous electrical activity in PON. Our results suggest that the use of semi-intact preparations allow elucidation of new functional cardioregulatory properties of intact neural networks.

Animals↗

Richter's hernia--a surgical pitfall.

BACKGROUND: Although Richter's hernia was first described in 1598, little attention has been given to this topic in recent literature. The diagnosis of Richter's hernia is difficult because of the innocuous development of signs and symptoms and it is associated with a high mortality rate. Awareness of this relatively rare surgical entity is important. STUDY DESIGN: Of 350 patients with incarcerated hernias who underwent operation between 1977 and 1994 at the Department of Surgery "A," Assaf Harofeh Medical Center, 14 had strangulated Richter's hernia. A retrospective study was carried out in order to characterize the clinical manifestations of Richter's hernia and to assess preoperative delay, hospital stay, and complication and mortality rates. A comparison study was made with matched patients with strangulated hernias of non-Richter's type. Differences in morbidity and mortality rates, preoperative delay, and hospital stay of patients with Richter's hernias and the comparison group were evaluated. RESULTS: Of 14 patients with Richter's hernia, seven underwent intestinal resection. The hernia most commonly occurred at the femoral and inguinal sites. Compared with patients with other hernias, patients with Richter's hernias had greater preoperative delay, rate of bowel resection, length of hospital stay, and postoperative morbidity and mortality rates. CONCLUSIONS: Early operative intervention is the mainstay of successful management of Richter's hernia and awareness of this disease and its misleading clinical presentation is of utmost importance.

Adult↗