Biomedical subjects

S Kann

Publications and source records attributed to S Kann.

6 recordsLinked to original sources

PubMed2004

17 Beta-estradiol regulates nNOS and eNOS activity in the hippocampus.

Estrogen treatment in symptomatic postmenopausal women appears to improve cognitive performance including memory, an effect which may involve enhanced nitric oxide formation in hippocampal neurons. To study whether 17beta-estradiol (E2) affects NO synthase activity in the hippocampus, we investigated the influence of E2 on hippocampal NO synthase expression and activity in female rats. Ovariectomy, which significantly decreased E2 serum levels, reduced neuronal (nNOS) and endothelial NO synthase (eNOS) expression and Ca(2+)-dependent NOS activity. E2 substitution reversed these effects. It is concluded that E2 increases nNOS and eNOS expression and activity in female hippocampus and thus improves hippocampal function.

Animals↗

PubMed2003

Vascular anatomy for right colon lymphadenectomy.

Since the superior mesenteric artery (SMA) mostly originates on the left side of the superior mesenteric vein (SMV), the ileocolic artery (ICA) and the right colic artery (RCA) cross the SMV. Understanding the three-dimensional relation of these vessels is important for dissecting these arteries to their origin. Hence, we conducted a study of the vascular anatomy of the right colon in 27 cadavers. The RCA was separate from the SMA in eight cases (30%). The RCA passed the SMV either anteriorly (5 cases, 63%) or posteriorly (3 cases, 38%). In seven (88%) of these eight cases, the ICA was posterior to the SMV. The ICA was identified in all 27 cases, and passed the SMV anteriorly in nine cases (33%) and posteriorly in 18 cases (67%). Thus, the ICA and the RCA may pass on either side of the SMV. The surgeon must dissect the arteries with the SMV, being aware of both possibilities.

Aged↗

PubMed2002

[Local and systemic symptoms after snake bite by a diamondback rattlesnake (Crotalus atrox)].

The incidence of snake bites grows more and more. The effects of the snake poison depend on the snake species. They can be cardio-, neuro-, myo-, tissue-, and/or cytotoxic, as well as hemorrhagically. In most cases a symptomatically therapy together with close controls of the labor parameters and a good monitoring is enough. Antivenom-therapy should be reserved for cases with strong indication.

Adult↗

PubMed1994

The "arthroscopic impingement test".

Arthroscopic acromioplasty is an effective technique to treat refractory impingement syndrome of the shoulder; however, it is a technically demanding procedure and failure due to inadequate acromial resection has been reported. The purpose of this study was to describe a more reliable technique of arthroscopic acromioplasty ("arthroscopic impingement test") that allows determination of subacromial space available (SSA) during shoulder flexion after acromioplasty. During a 2-year period, 70 consecutive patients (group I) underwent arthroscopic acromioplasty by a conventional technique and 50 consecutive patients (group II) underwent the modified technique. Both groups were comparable in terms of age, gender, chronicity of symptoms, incidence of workman's compensation cases, side of surgery, and operative findings. In group I, four patients (6%) failed due to inadequate acromioplasty and at time of revision were found to have 0 mm SSA at 120 degrees flexion (contact of cuff on acromion). After revision acromioplasty, SSA at 120 degrees flexion was measured as > 3 mm, and impingement symptoms resolved postoperatively. In group II, there were no failures and SSA after initial acromioplasty was found to average 13 mm at 0 degree 10 mm at 45 degrees, 8 mm at 90 degrees, and 6 mm at 120 degrees flexion. In four cases, the "arthroscopic impingement test" determined that there was inadequate SSA at 120 degrees (< 3 mm) after initial acromioplasty, and these were revised by further acromioplasty at time of surgery. It was concluded that the "arthroscopic impingement test" improves reliability of arthroscopic acromioplasty by verifying adequate acromial resection in a position of impingement.

Acromion↗

PubMed1994

Arthroscopic repair of combined Bankart and superior labral detachment anterior and posterior lesions: technique and preliminary results.

Over a 3-year period nine of 585 patients undergoing shoulder surgery were found to have a superior labral detachment anterior and posterior (SLAP) lesion. Seven patients also had an associated Bankart lesion and underwent arthroscopic repair of the entire anterior-inferior-superior-posterior labral detachment using the Suretac (Acufex Microsurgical Inc., Mansfield, MA) fixation device. The technique used requires an accessory anterior-lateral portal to access the superior-posterior labral detachment and an accessory anterior-inferior portal to access the Bankart lesion. Three to four Suretacs were required for repair in these cases. At an average follow-up of 19 months (range 15-22), five of seven patients had no pain, full range of motion, and a full premorbid activity level. One patient redislocated at 4 months postoperatively and was successfully managed with an open repair, and one patient developed a stiff shoulder that was successfully managed with arthroscopic release and manipulation. We conclude that this arthroscopic technique is a useful method to manage extensive labral detachment in selected patients.

Adolescent↗

PubMed1989

[Acoustic neurinoma presenting with repeated intratumoral hemorrhage. Case report].

A case of acoustic neurinoma with multiple intratumoral hemorrhages is reported. A 56-year-old male noted sudden hearing reduction in his left ear in October of 1985. The diagnosis of a local physician was sudden deafness. About 10 months later, he had two episodes of severe headache without nausea or vomiting. The patient was hospitalized in October of 1986. Neurological examination cerebellar ataxia. cerebellar ataxia. Plain and enhanced computed tomography revealed only an unremarkable low-density area at the left cerebellopontine angle. In contrast, magnetic resonance imaging (MRI) clearly demonstrated a large (3 x 4 x 5 cm), multicystic tumor in the site. On exposure of the tumor at surgery, most of the cysts were found to be filled with a dark red or xanthochromic fluid. The tumor was completely removed following numerous cyst punctures to decrease its volume. There was no evidence of subarachnoid hemorrhage. Histological examination showed a typical acoustic neurinoma. The cyst wall contained numerous telangiectasia-like lesions. The initial symptom of this patient was sudden hearing loss, which is an atypical manifestation of acoustic neurinoma. The massive intratumoral hemorrhage was thought to be caused by telangiectatic lesions in the cyst wall. MRI clearly demonstrated the hemorrhagic cysts within the tumor, especially in the posterior fossa.

Cerebellar Neoplasms↗