PubMed Health⌕ Search

Biomedical subjects

S Karan

Publications and source records attributed to S Karan.

At least 19 recordsLinked to original sources
PubMed2000

Congenital methemoglobinemia.

A case of congenital methemoglobinemia presenting at birth is reported. The clinical signs, differential diagnosis, pathogenesis and management of this disorder are discussed.

Humans↗
PubMed1997

Severe and complicated malaria in Bikaner (Rajasthan), western India.

Severe and complicated malaria is an important cause of mortality in Plasmodium falciparum infection. We describe in this study the details of 532 cases of such syndromes admitted to hospital during an outbreak of malaria between September-December 1994. Increase in the annual rain fall, collection of water around Indra Gandhi Canal, forestation of shrubs around it and migration of labor, adaptation of Anopheles stephensi to desert climate and favorable breeding of An. culicifacies in the areas under impact of irrigation were presumptive causes of the outbreak in this region. Cerebral malaria (25.75%), hepatic involvement (11.47%), spontaneous bleeding (9.58%), hemoglobinuria (7.89%), severe anemia (5.83%), algid malaria (5.26%), ARDS (3%) and renal failure (2.07%) were the important manifestations. The overall mortality was 11.09%, which was high because of infection in the non-immune population of this area. Ignorance about the severity of this disease and lack of transportation facility was another important factor. Morality was highest in ARDS (81.25%) followed by severe anemia (70.97%), algid malaria (46.43%), renal failure (45.45%), jaundice (36.06%) and cerebral malaria (33.57%). Pregnancy was an important determinant increasing the mortality in female patients. Mortality was very high (82.35%) in those persons who presented with more than 3 syndromes together.

Acute Kidney Injury↗
PubMed1986

Purulent meningitis in the newborn.

Neonatal meningitis is characterized by unusual clinical manifestations caused by unusual organisms (with a marked predominance of gram-negative organisms), a poor prognosis due to the failure of antibiotics to penetrate the blood-brain barrier, and frequent complications (ventriculitis, hydrocephalus, and brain damage). The literature is reviewed and our personal experience described. The clinical and bacteriological findings, the complications and results of various therapeutic regimes, and the factors affecting prognosis are discussed.

Ampicillin↗