PubMed HealthSearch

Biomedical subjects

S Karl

Publications and source records attributed to S Karl.

6 recordsLinked to original sources

[Dermatologic climate therapy--definition, indications and public health necessity].

Dermatological climatotherapy is used in the treatment of chronic and chronically relapsing long-term dermatoses, such as, especially, atopic dermatitis and psoriasis, complementing the dermatological therapies applied at the patient's place of living. It is a classical dermatological in-clinic therapy carried through in specific rough and stimulating climate areas of proven therapeutic benefit, primarily the North Sea climate and certain alpine locations over 1 500 m above sea-level, like especially in the high mountain valley of Davos, Switzerland. Dermatological climatotherapy is a well-tried therapeutic agent which, in comparison to the dermatological therapies applied at home, as a rule has fewer side effects as well as, above all, an additional long-lasting time effect. The latter is of particular importance regarding chronical diseases and cannot be achieved by other therapies. Dermatological climatotherapy, hence, represents an all-entailing therapy form and moreover is the most comprehensive therapy anyway. Dermatological climatotherapy can only be performed in rough and stimulating climate zones with additional special insolation, thermichygric and defined aerosol conditions. On the one hand, the organism is stabilized general by those climatic conditions, and, on the other, the constitutionally damaged skin is affected positively by the direct influence of climate factors. As every climate has its specific overall effect, the therapeutical immediate and long-term effects of a climate have to be proven scientifically by follow-up studies.

Acclimatization

[Hyposensitization with cross-reacting pollen allergens].

Grass-pollen are one of the most common allergens in pollinosis. Rye-pollen are the most important allergens among cereals-pollen in Germany. Between pollen-allergens, the phenomenon of cross-sensitivity is well-known. In the RAST und RAST-Inhibitionstest the cross-sensitivity between grass-pollen and rye-pollen is well documentated. In the clinic the test and challenge with some grass-pollen ist suitable for the diagnosis and planing of therapy. Therefore, it seems, that therapy with grass-pollen should produce the same results as a treatment with grass- and rye-pollen. We treated 35 patients allergic with poaceae-pollen for 3 years in two different ways: One group we treated only with grass-pollen, the other group we treated with grass- and rye-pollen. Under the therapy we controlled the specific IgE and IgG, the nasal challenge-test and the subjective symptoms by diaries and questionnaires. The specific IgE for phleum pratense and rye-pollen decreased, the specific IgG increased in both groups. There were no differences between the two therapy-groups. In the clinical data-subjective and nasal challenge-the therapeutic effect seemed to be better in the group treated with grass- and rye-pollen.

Adult